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ENDOTHELIUM-DERIVED NITRIC OXIDE AND EXERCISE INDUCED VASODILATION

ENDOTHELIUM-DERIVED NITRIC OXIDE AND EXERCISE INDUCED VASODILATION
内皮源性一氧化氮和运动引起的血管舒张
批准号：
3779640
负责人：
A A QUYYUMI
金额：
$0.0万
依托单位：
NATIONAL HEART, LUNG, AND BLOOD INSTITUTE
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/3779640
关键词：
exercise human subject nitric oxide vasodilatation vasodilators

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中文摘要
翻译
血管(内皮)的内层能够释放一种 一种名为内皮衍生松弛因子的物质，它会导致 血管的松弛。内皮细胞来源的持续释放 松弛因子维持低血管张力。以调查是否 这一因子的释放对血液的松弛也很重要。 伴随肌肉运动的血管，我们调查了 血管内皮源性松弛因子释放的阻滞剂对血管紧张素转换酶的影响 患者进行前臂锻炼。高达25%的血液松弛 运动中发生的血管是由于内皮细胞的释放- 衍生的松弛因子，表明这种物质起着重要作用 在运动的生理学方面。
英文摘要
The lining of blood vessels (endothelium) is capable of releasing a substance called endothelium-derived relaxant factor which causes relaxation of blood vessels. Continuous release of endothelium-derived relaxant factor maintains a low blood vessel tone. To investigate if the release of this factor is also important in causing relaxation of blood vessels that accompanies exercise of the muscle, we investigated the effect of a blocker of release of endothelium-derived relaxant factor in patients during forearm exercise. Up to 25% of the relaxation of blood vessels that occurs during exercise is due to release of endothelium- derived relaxant factor, suggesting an important role for this substance in the physiology of exercise.
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会议论文
EFFECTS OF ENDOTHELIUM-DERIVED RELAXANT FACTOR ON CORONARY RESISTANCE VESSELS
CIRCADIAN VARIATION IN ISCHEMIC THRESHOLD AND VASCULAR RESISTANCE IN CAD
EFFECT OF L-ARGININE ON ENDOTHELIUM-DEPENDENT CORONARY VASOMOTION
PLATELET INHIBITORY EFFECT OF ENDOTHELIUM-DERIVED RELAXING FACTOR
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