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STUDIES OF PATIENTS WITH IMMUNE-MEDIATED DISEASES

STUDIES OF PATIENTS WITH IMMUNE-MEDIATED DISEASES
对免疫介导疾病患者的研究
批准号：
3804550
负责人：
A D STEINBERG
金额：
$0.0万
依托单位：
NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/3804550
关键词：
6 thioguanine T lymphocyte antibody formation cellular immunity human subject immunoregulation systemic lupus erythematosus tissue /cell culture

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中文摘要
翻译
系统性红斑狼疮患者被发现突变增加 在他们的T细胞中，定义为他们在存在的情况下生长的能力 6-硫代鸟嘌呤。这在多大程度上是由主节点 异常情况和药物的作用程度仍有待观察 下定决心。
英文摘要
Patients with systemic lupus were found to have an increase in mutations in their T cells as defined by their ability to grow in the presence of 6-thioguanine. The extent to which this results from a primary abnormality and the extent to which drugs contribute remains to be determined.
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会议论文
ANTINUCLEAR ANTIBODIES IN SPONTANEOUS AND DRUG-INDUCED SLE AND OTHER DISEASES
PATHOGENESIS OF AUTOIMMUNITY IN MICE WITH SLE-LIKE ILLNESS
VARIOUS CYTOTOXIC DRUG PROGRAMS IN DIFFUSE LUPUS NEPHRITIS
IMMUNE ABNORMALITIES IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS
海外基金