PATIENT RESPONSE TO RESUMPTION OF NEUROLEPTICS FOLLOWING A DRUG FREE INTERVAL

研究表明，精神分裂症患者对康复治疗有反应 抗精神病药的特征模式，但对 症状变化的潜在机制。为了澄清这个问题， 行为和症状变化的双盲系列测量 精神分裂症受试者在一段时间后恢复服用抗精神病药物 对戒毒期进行分析。50%的回复发生了 在药物恢复后的第七天，包括显著的 症状/行为量表测量妄想症的子量表的改进， 幻觉和其他与精神病相关的阳性症状。

Studies have shown that schizophrenics respond to the reinstatement of neuroleptics in a characteristic pattern, but there is disagreement about the mechanism underlying symptom change. To clarify this issue, double-blind, serial measurements of the behavior and symptom change of schizophrenic subjects who resumed neuroleptic medication after a drug-free period were analyzed. Fifty percent of the response occurred by the seventh day of post-drug reinstatement, including a significant improvement in symptom/behavior inventory subscales measuring delusions, hallucinations, and other positive symptoms associated with psychosis.