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EFFECT OF APO A-IV-2 ALLELE ON THE RESPONSE TO DIETARY FAT AND CHOLESTEROL

EFFECT OF APO A-IV-2 ALLELE ON THE RESPONSE TO DIETARY FAT AND CHOLESTEROL
APO A-IV-2 等位基因对膳食脂肪和胆固醇反应的影响
批准号：
6282766
负责人：
RICHARD B WEINBERG
金额：
$3.63万
依托单位：
WAKE FOREST UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
1997
资助国家：
美国
项目状态：
已结题
起止时间：
1997-12-01 至 1998-11-30
来源：
https://reporter.nih.gov/project-details/6282766
关键词：
alleles apolipoproteins cholesterol clearance rate clinical research clinical trials dietary lipid gastrointestinal nutrient absorption gene expression human subject hypercholesterolemia lipid metabolism nutrition related tag triglycerides

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中文摘要
翻译
人体对膳食胆固醇的反应变化很大。的影响
英文摘要
The human response to dietary cholesterol is highly variable. The impact of the variant allele apo A-IV-2 on the response to dietary saturated fat and the mechanisms of the allele are unknown. Dr. Weinberg proposes a matched, controlled dietary trial with lipid measurement, fractional cholesterol absorption and post-prandial triglyceride clearance. Defining the effect of the apo A-IV-2 allele on diet-induced hypercholoesterolemia will further elucidate the impact of genetics on cholesterol metabolism.
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