CELL MIGRATION AND INVASION

细胞迁移和侵袭在胚胎发育、炎症、细胞移植和肿瘤转移等重要的生理和病理现象中起着核心作用。细胞迁移还提供了一个可访问的模型，用于理解单个细胞如何作为集成系统发挥作用，并解释其环境中的多个复杂信号。在理解细胞迁移和侵袭的分子基础方面正在取得实质性进展。示例包括：阐明所涉及的受体和信号转导途径，鉴定调节粘连形成和释放的途径，开发用于观察体内细胞和分子动力学的技术，以及阐明调节作用聚合和组织的机制。本次会议的目的是汇集研究人员的迁移的基本机制与那些感兴趣的迁移和入侵在特定疾病中的作用，并在制定治疗策略。这将是5年来第一次研究人员，包括移民的子学科的研究人员将一起开会。

Cell migration and invasion plays a central role in important physiological and pathological phenomena including embryonic development, inflammation, cellular transplantation and tumor metastasis. Cell migration also provides an accessible model for understanding how individual cells function as integrated systems and interpret multiple, complex signals in their environment. Substantial progress is being made in understanding the molecular basis of cell migration and invasion. Examples include: elucidation of the receptors and signal transduction pathways involved, identification of the pathways that regulate the formation and release of adhesions, development of technologies for observing cellular and molecular dynamics in vivo, and elucidation of the mechanisms that regulate action polymerization and organization. The goal of this meeting is to bring together investigators studying basic mechanisms of migration with those interested in the role of migration and invasion in specific diseases and in developing therapeutic strategies. This will be the first time in 5 years investigators that investigators in the subdisciplines that comprise migration will meet together.