Training Program in the Molecular Bases of Eye Disease

描述：(申请者摘要)博士后培训计划 促进了解决眼病潜在分子基础的研究 是由哈佛医学院眼科创建的。 该计划旨在提供最新分子方面的专业知识 研究技术，并使受训人员具备以下知识 眼科存在的突出问题。32名教职员工导师，他们都有 哈佛大学眼科系的任命或从属关系 来自马萨诸塞州眼耳科的实验室 医务室、谢彭斯眼科研究所、布里格姆和妇女医院 医院、朗伍德校区基础科学系和 剑桥大学校园里的分子和细胞生物学。这些导师指挥 资金充足的项目，眼科和视力研究的研究机会 使用当前的分子技术，并拥有一流的设施。自1997年以来， 培训计划启动时，有10名学员 在过去的一个月里，有3名新的实习生被录取。每个人 学员预计将接受两到三年的培训。实习生(一) 参加全日制研究，掌握分子技术 应用于生物化学、细胞生物学、遗传学、免疫学或神经生物学 眼科和视力；(Ii)接受眼科问题培训 通过一系列教学课程、临床大轮回、研讨会、期刊 俱乐部、会议；以及(3)撰写和提交赠款建议书，以获得 对第二年和第三年培训的个人支持，在 关于拨款申请原则的正式课程。在此续签申请中， 我们寻求支持，将我们的计划再延长五年。我们建议 在此期间，将每年接纳的实习生人数增加到9人 期间，并扩大申请者池，以包括拥有 完成了他们的眼科训练。我们的目标是培养下一代 新一代调查人员能够解决诊断、预防、 以及眼科疾病的治疗。

DESCRIPTION: (Applicant's Abstract) A postdoctoral training program that fosters research addressing the underlying molecular basis of eye diseases has been created through the Department of Ophthalmology at Harvard Medical School. The program is designed to provide expertise in the most current molecular research techniques and to equip the trainees with a knowledge of the outstanding problems in ophthalmology. Thirty-two faculty mentors, all with appointments or affiliations with the Department of Ophthalmology at Harvard Medical School, are drawn from laboratories of the Massachusetts Eye and Ear Infirmary, the Schepens Eye Research Institute, the Brigham and Women's Hospital, the Longwood Campus Basic Science Departments and the Department of Molecular and Cellular Biology on the Cambridge Campus. These mentors command well funded programs, research opportunities for ophthalmic and vision research using current molecular techniques, and have excellent facilities. Since 1997, when the Training Program was initiated, 10 trainees have matriculated, and 3 new trainees have been admitted within the past month. Each trainee is expected to spend two to three years in training. Trainees (i) participate in full-time research to obtain a mastery of molecular techniques in biochemistry, cell biology, genetics, immunology, or neurobiology as applied to ophthalmology and vision; (ii) acquire training in ophthalmic problems through a series of didactic courses, clinical grand rounds, seminars, journal clubs, meetings; and (iii) write and submit grant proposals to obtain individual support for second and third year of training under the guidance of a formal course in principles of grant submission. In this renewal application, we seek support to extend our program for five additional years. We propose to increase the number of trainees admitted per year to 9 over the course of this period, and to expand the applicant pool to include MDs and DVMs who have completed their ophthalmology training. Our goal is to train the next generation of investigators who can address problems of diagnoses, prevention, and treatment of diseases of the eye.