Molecul Biology of Intestinal Lipid Transport/Metabolism

描述（由申请人提供）： FASEB肠道脂质转运和代谢分子生物学夏季会议将汇集各种相关领域的科学家，旨在定义，描述和分析关键的科学问题以及亲密和互动环境中的最新进展。这次会议的一个主要特点是有机会促进学生和博士后研究员与该领域的高级知名人士的互动。历史上，这种互动在确定新的研究议程和促进科学讨论与合作方面取得了成功。本申请要求为将于2003年8月3日至7日在科罗拉多斯诺马斯的斯诺马斯村举行的会议提供部分资金。这将是关于这一主题的第五次此类会议;上一次是在2000年夏季举行的。这次会议是独特的，在其高度多学科的方法，并在其重点放在一个未充分研究的主题。因此，我们将汇集一组具有营养，生理学，生物化学，蛋白质化学，细胞和分子生物学以及发育生物学领域专业知识的高级和初级研究人员，以解决脂质代谢的最新进展，因为它们与肠道有关。会议形式将包括七个主要的口头会议，安排在四天（上午四点和下午三点），一个晚上的主题演讲和两个海报会议。到目前为止，已有26名受邀发言者确认了参加的愿望。 七场正式会议重点关注活跃的研究领域：1）固醇吸收和转运; 2）肠道胆汁酸和视黄醇转运; 3）脂肪酸转运蛋白; 4）与细胞内脂质组装相关的酶; 5）脂质代谢的转录控制; 6）脂蛋白组装和代谢的分子遗传学;和7）肝脏脂质代谢和分泌的综合调节。所有与会者将被邀请提交一份摘要，将在会议期间举行的两个海报会议之一，以允许所有与会者，特别是学生和初级研究人员提出数据，并参与讨论。将从提交的摘要中选择其他发言者，并鼓励所有与会者提交特别新颖的最新发展，以“热门话题”的形式进行简短的口头介绍。这些热门话题会议将专门针对年轻科学家。在过去，该会议促进了来自学术界和工业界的基础和临床研究人员之间的互动和科学讨论。有限的出席人数，最先进的科学会议，“热门话题”的补充，和新颖的海报介绍联合收割机相结合，提供了一个重要的论坛，将进一步在一个领域，这是在很大程度上缺乏其他会议和国家场馆的科学进步。

DESCRIPTION (provided by applicant): The FASEB Summer Conference on the Molecular Biology of Intestinal Lipid Transport and Metabolism will bring together scientists in a variety of related fields with the purpose of defining, describing and analyzing critical scientific problems and recent advances in an intimate and interactive environment. A key feature of this meeting is the opportunity to facilitate the interactions of students and postdoctoral fellows with senior established figures in the field. Such interactions have historically been successful in defining new research agendas and fostering scientific discourse and collaborations. This application requests partial funding for a Conference to be held August 3-7, 2003 at Snowmass Village in Snowmass, Colorado. This will be the fifth such conference on this theme; the last one was held in the summer of 2000. This conference is unique in both its highly multidisciplinary approach and in its focus on an understudied topic. Thus, we will bring together a diverse group of senior and junior investigators with expertise in the areas of nutrition, physiology, biochemistry, protein chemistry, cell and molecular biology, and developmental biology, to address recent advances in lipid metabolism as they relate to the intestine. The format will consist of seven major oral sessions scheduled over four days (four AM and three PM), an evening Keynote Address and two poster sessions. To date 26 invited speakers have confirmed their desire to participate. The seven formal sessions focus on active research areas: 1) Sterol absorption and transport; 2) Intestinal bile acid and retinol transport; 3) Fatty acid transporters; 4) Enzymes associated with intracellular lipid assembly; 5) Transcriptional control of lipid metabolism; 6) Molecular genetics of lipoprotein assembly and metabolism; and 7) Integrated regulation of hepatic lipid metabolism and secretion. All participants will be invited to submit an abstract to one of two poster sessions that will be held during the conference in order to allow all attendees, especially students and junior investigators to present data and participate in discussions. Additional speakers will be chosen from the abstract submissions, and all participants will be encouraged to submit particularly novel late-breaking developments for brief oral presentation in the form of "hot topics". These hot topics sessions will be targeted specifically to accommodate junior scientists. In the past this conference has promoted interactions and scientific discussions among basic and clinical investigators from academia and industry. The limited attendance, state of the art scientific sessions, "hot topics" additions, and novel poster presentations combine to provide an essential forum that will further scientific advances in a field that is largely underserved by other conferences and national venues.