New Synthetic Methods for Anticancer Research

超出提供的空间。最简单的方法是使核心结构更容易被各种取代基取代。正是在总体上支持健康科学，里面提出的化学找到了它的意义。由于过渡金属物种在非常温和的条件下影响碳-碳和碳-杂原子键的形成的独特能力，本提议的重点是使用有机过渡金属化学来促进各种转化。提出的化学的一个基本主题是开发灵活的新的合成方法，这些方法将促进结构-活性-关系的研究，从而导致新的药物的发现。演出现场(S)(组织、市、州)埃默里大学化学系1515皮尔斯大道佐治亚州亚特兰大市30322名关键人员。请参阅说明。根据需要使用续页，以在《与主要调查者一起开始》中提供所需信息。按字母顺序列出所有其他关键人员，姓氏在前。名称组织利贝斯金德，兰尼·S·埃默里大学索尔，吉日·埃默里大学披露许可声明。仅适用于SBIR/STTR。请参阅说明。[]是[]否小灵通398(05/01版)在整个申请过程中，第2页在底部连续编号。不要这样做，如3a，3b。格式如下所示。项目首席调查员St.Research Associate表单第2页========================================Section End===========================================的角色

EXCEED THE SPACE PROVIDED. Ayest apofowuenrfdualtionmethuopdosn wfohricthe nseywnthmeseidsicinoafl coaregenotrsganciacn fbuencctionsatlriutiectse,d, asit wiselilmpaosrtmanetthotdos untchoavteralloswimptlhee, core structures to be easily substituted with a wide variety of substituents. It is in support of health sciences in general that the chemistry proposed within finds its significance. Because of the unique ability of transition metal species to effect the formation of carbon-carbon and carbon-heteroatom bonds under very mild conditions, emphasis in this proposal is placed on the use of organotransition metal chemistry to facilitate a variety of transformations. An underlying theme of the )roposed chemistry is the development of flexible new synthetic methods that will facilitate the structure-activity-relationship studies that lead to the discovery of new medicinal agents. PERFORMANCE SITE(S) (organization, city, state) Emory University Department of Chemistry 1515 Pierce Drive Atlanta, Georgia 30322 KEY PERSONNEL. See instructions. Use continuation pages as needed to provide the required information in the Start with Principal Investigator. List all other key personnel in alphabetical order, last name first. Name Organization Liebeskind, Lanny S. Emory University Srogl, Jiri Emory University Disclosure Permission Statement. Applicable to SBIR/STTR Only. See instructions. [] Yes [] No PHS 398 (Rev. 05/01) Page 2 Number pages consecutively at the bottom throughout the application. Do no._u_sLet suffixessuch as 3a, 3b. format shown below. Role on Project Principal Investigator St. Research Associate Form Page 2 ========================================Section End===========================================