Finding the missing katanin required for male fertility
Finding the missing katanin required for male fertility
批准号:
nhmrc : 1138014
负责人:
Prof Moira O'Bryan
金额:
$28.21万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2018
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2018-01-01 至 2020-12-31
中文摘要
微管是所有细胞的关键元素,包括男性生殖细胞。在这个项目中,我们将确定微管切割蛋白KATNA1在男性生育中的功能。这将使用独特的模型和最先进的技术来实现。该项目将与每20名患有不孕症的澳大利亚男性中就有1名直接相关,但也将告知KATNA1在产生KATNA1的许多其他组织中的功能。
英文摘要
Microtubules are a key element of all cells, including in the male germ line. In this project we will define the function of the microtubule severing protein KATNA1 in male fertility. This will be achieved using a unique model and state-of-the-art technologies. This project will have immediate relevance to the 1 in 20 Australian men who suffer from infertility but will also inform KATNA1 function in the many other tissues where KATNA1 is produced.
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会议论文
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依托单位:
Finding the missing katanin required for male fertility
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批准号:nhmrc : GNT1138014
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项目类别:Project Grants
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资助金额:$41.72万
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财政年份:2018
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负责人:Prof Moira O'Bryan
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依托单位:
The genetic causes of male infertility
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财政年份:2017
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A novel microtubule severing protein involved in male germ cell biology
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财政年份:2016
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负责人:Prof Moira O'Bryan
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依托单位:
Male fertility and health
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批准号:nhmrc : GNT1058356
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项目类别:Research Fellowships
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财政年份:2014
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负责人:Prof Moira O'Bryan
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依托单位:
Male germ cell development - fertility and health
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批准号:nhmrc : 1058356
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项目类别:Research Fellowships
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资助金额:$50.9万
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财政年份:2014
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负责人:Prof Moira O'Bryan
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依托单位:
HEN1 is a regulator of piRNA metabolism, transcriptional regulation and mammalian male fertility
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财政年份:2012
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A novel DNA damage repair protein as a regulator of DNA double strand break repair and genome integrity
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财政年份:2011
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负责人:Prof Moira O'Bryan
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依托单位:
Uncoupled Research Fellowship
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财政年份:2009
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负责人:Prof Moira O'Bryan
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依托单位:
The identification of male meiosis genes using a new mouse line and human genome scans for gene copy number variations
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财政年份:2008
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负责人:Prof Moira O'Bryan
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依托单位:
Research Fellowship - Grant ID:384132
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批准号:nhmrc : 384132
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项目类别:NHMRC Research Fellowships
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资助金额:$21.52万
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财政年份:2006
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依托单位:
The Biology of Sperm Tail Development
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财政年份:2001
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依托单位:
The expression and regulation of nitric oxide synthases in the male reproductive tract
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依托单位:
国内基金
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批准年份:2011
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Missing in Metastasis基因在子宫内膜癌转移中的机制
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批准号:81060175
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批准年份:2010
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依托单位: