Houston Area Molecular Biophysics Program

描述(由申请人提供)：休斯顿地区分子生物物理学项目(HAMBP)是一个分子生物物理学博士研究培训项目，有52名教师参加，他们来自休斯顿-加尔维斯顿地区的六个教育/研究机构：贝勒医学院、莱斯大学、休斯顿大学、德克萨斯大学休斯顿医学院、德克萨斯大学M.D.安德森癌症中心和德克萨斯大学医学分校。由于这类院校的教员人数众多，申请者众多，我们建议将我们资助的学员人数增加到12人。学生在课堂和实验室都要进行严格的课程学习。他们在分子生物物理学的基础上获得了坚实的基础，接触到了广泛的主题，并在世界级的生物物理实验室进行前沿的论文研究。研究领域包括X射线结晶学、大分子电子显微镜、荧光、磁共振等类型的大分子光谱学、热力学、动力学、分子动力学、理论生物物理学、蛋白质折叠、核酸结构、分子识别等。所研究的生物结构的大小从多肽和脂质介体到病毒、转录复合体和肌丝。受资助的学员包括4个代表性不足的少数民族，他们的平均GRE分数分别为83%(Q)、81%(A)、79%(V)和71%(ADV.)，本科平均GPA为3.55/4.0。过去的学员平均每名学员的出版物数量为6.4篇，所有学员的平均出版物数量为4.6篇，包括许多备受瞩目的论文和期刊封面。校友在完成培训后获得了优秀的职位，并继续进行高水平的研究。该计划由来自所有伙伴机构的代表组成的指导委员会管理，该委员会密切监测受训人员的进展，并就申请学生和导师的录取做出决定。HAMBP是合作机构的几个非常成功的合作培训和研究项目之一，这些合作机构的研究资源和受训人员加起来比美国任何一家机构都要大。

DESCRIPTION (provided by applicant): The Houston Area Molecular Biophysics Program (HAMBP) is a Ph.D. research training program in molecular biophysics involving 52 faculty mentors in six educational/research institutions in the Houston-Galveston area: Baylor College of Medicine, Rice University, University of Houston, University of Texas-Houston Medical School, University of Texas M.D. Anderson Cancer Center, and University of Texas Medical Branch. Because of the large number of faculty, and the large and diverse applicant pool represented by this group of institutions, we propose to increase our number of funded trainees to 12. Students pursue a rigorous course of study in the classroom and in the laboratory. They receive a strong foundation in the fundamentals of Molecular Biophysics, exposure to a broad range of topics, and pursue cutting-edge thesis research in world-class biophysics laboratories. Research areas include x-ray crystallography, macromolecular electron microscopy, fluorescence, magnetic resonance and other types of macromolecular spectroscopy, thermodynamics, kinetics, molecular dynamics, theoretical biophysics, protein folding, nucleic acid structure, molecular recognition, and others. Biological structures studied range in size from peptides and lipid mediators to viruses, transcription complexes, and muscle filaments. Supported trainees have included 4 underrepresented minorities, and have had average GRE scores of 83%tile (Q), 81%tile (A), 79%tile(V), and 71%tile (Adv.), with average undergraduate GPAs of 3.55/4.0. The average number of publications per trainee is 6.4 for past trainees, and 4.6 for all trainees, including many high-profile papers and journal covers. Alumni have secured excellent positions upon completion of training, and continue to perform research at a high level. The Program is administered by a Steering Committee of representatives from all partner institutions, which closely monitors the progress of trainees, and make decisions about admission of applicant students and mentors. HAMBP is one of several highly successful cooperative training and research ventures of the partner institutions, which together represent a larger pool of research resources and trainees than any single institution in the U.S.