EPISODIC MEMOERY IN RHESUS MONKEYS SPATIAL & TEMPORAL CONTEXTS

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。所列机构为中心，不一定是研究者所在机构。人类的意识记忆分为两种类型。语义记忆由关于世界的事实组成：沙漠中缺水，海鲜必须新鲜才安全。情景记忆还有助于回忆自传体事件：在沙漠徒步旅行中，水用完了;在海滩派对上，你被变质的蛤蜊弄得恶心。虽然许多实验表明猴子和其他动物都有记忆，但事实证明，在非人类中很难区分语义记忆和情景记忆。开发区分猴子这两种记忆的程序将使我们能够更有效地利用非人类模型系统来理解正常的人类认知和影响它的疾病。觅食实验室里的记忆测试猴子已经学会了离开运输笼，进入一个大房间，翻转塑料花盆寻找食物，而项圈上系着皮带。猴子刚刚开始在这种环境中进行样本匹配训练。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Conscious memory in humans is divided into two types. Semantic memory consists of facts about the world: water is scarce in the desert, seafood must be fresh to be safe. Episodic memory sub-serves the ability to recall autobiographical events: once running out of water on a desert hiking trip, the time you were sickened by spoiled clams at a beach party. While many experiments show that monkeys and other animals remember, it has proven difficult to make this important distinction between semantic and episodic memory in nonhumans. Developing procedures for distinguishing between these two types of memory in monkeys will permit us to make more effective use of nonhuman model systems for understanding normal human cognition and the diseases that affect it. We have begun training monkeys in a large open-field ?foraging? memory test in the lab. Monkeys have learned to exit their transport cage, enter a large room, and flip over plastic flower pots looking for food while a leash is attached to their collar. Monkeys have just begun matching to sample training in this environment.