COBRE: WVU: SIGNAL TRANSDUCTION & CANCER: FLOW CYTOMETRY CORE FACILITY

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。所列机构为中心，不一定是研究者所在机构。西弗吉尼亚大学（WVU）流式细胞术核心设施成立于2002年，是信号转导和癌症生物医学研究卓越中心（COBRE）资助的一部分。流式细胞仪核心设施为西弗吉尼亚大学和邻近机构提供分析流式细胞仪和细胞分选，并支持COBRE研究人员以及其他NIH资助的项目。在过去的3年里，该设施支持的研究导致了23篇同行评审的出版物和20多篇摘要。本申请描述了1）该设施的历史，目前的仪器和人员，2）核心设施的运作计划，3）在实现COBRE-funded和其他项目在西弗吉尼亚大学的研究目标的核心设施的贡献，4）该设施？在当前和未来的癌症相关项目中的作用，包括COBRE资助更新申请中描述的研究项目，以及5）关于为最先进的细胞FACSAria细胞分选器获得资金的成功努力的报告。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The West Virginia University (WVU) Flow Cytometry Core Facility was established in 2002 as part of the Center for Biomedical Research Excellence (COBRE) grant in Signal Transduction and Cancer. The Flow Cytometry Core Facility offers analytic flow cytometry and cell sorting to WVU and neighboring institutions, and supports COBRE investigators as well as other NIH-funded projects. In the past 3 years the facility has supported research leading to 23 peer-reviewed publications and over 20 abstracts. This application describes 1) the Facility¿s history, current instrumentation, and personnel, 2) the Core Facility Operational Plan, 3) the contribution of the Core Facility in fulfilling research objectives of COBRE-funded and other projects at WVU, 4) the Facility¿s role in current and future cancer-related projects including research projects described in the COBRE grant renewal application, and 5) a report on successful efforts at obtaining funding for a state of the art cell FACSAria cell sorter.