OK COBRE: NUCLEIC ACID ANALYSIS CORE

这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金，因此可能会出现在其他CRISE条目中。列出的机构是针对中心的，而不一定是针对调查员的机构。核酸分析核心的目标是为Cobre研究人员提供资源和专业知识，以在核酸水平上研究分子机制。为了实现这些目标，CORBE的研究人员可以获得专门的设备、培训和开发以及实验设计。这些能力组装在核酸分析核心中，为初级调查人员提供了一个单一的切入点，为操纵核酸的实验的技术方面提供了全面的建议(指导)，获得了训练有素的技术人员，以及非常复杂和昂贵的设备。核心将提供分析开发、数据收集或核苷酸合成。这一核心集中了高效和可靠地产生高质量核酸分析数据所需的设备和经验。通过该核心提供的服务包括DNA测序、单核苷酸多态(SNP)基因分型、小鼠和人的表达阵列以及SNP阵列。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The goal of the Nucleic Acid Analysis Core is to provide COBRE investigators with resources and expertise to study molecular mechanisms at the nucleic acid level. To meet these goals, CORBE investigators are given access to specialized equipment, training and development, and design of experiments. The capabilities, assembled in the Nucleic Acid Analysis Core, provide the Junior Investigators a single point of entry, comprehensive advice (mentoring) for the technical aspects of experiments manipulating of nucleic acids, access to highly-trained technical personnel, and very sophisticated and expensive equipment. The Core will offer assay development, data collection, or nucleotide synthesis. This Core centralizes the equipment and experience needed to efficiently and reliably produce high quality nucleic acid analysis data. The services available through this Core include DNA sequencing, single nucleotide polymorphism (SNP) genotyping, expression arrays in mouse and man, and SNP arrays.