MICHIGAN INSTITUTE CTSA FOR CLINICAL TRIALS

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 密歇根大学临床和转化科学奖（UM CTSA）将重点关注世界上最优秀的研究机构之一在支持和促进临床和转化“团队科学”方面的强大优势。UM CTSA将被安置在新成立的密歇根临床和健康研究所（MICHR）。MICHR由大学创建，以最大限度地发挥一个非常支持跨学科研究并在健康科学方面具有巨大优势的机构的潜力。MICHR在大学的相关单位，NIH，外部行业合作伙伴和社区之间建立了伙伴关系。绝大多数的UM学校，学院和研究所都参加了，包括顶级的商学院，牙科，医学，护理，社会工作和公共卫生学院，工程学院，药学院，文学，科学和艺术学院，运动机能学系，社会研究所和生命科学研究所。大学拥有的卫生系统，其中包括综合门诊和住院设施，大大有助于与UM CTSA的强有力的伙伴关系。MICHR的主任是UM CTSA赠款的PI，并向大学执行副校长报告，后者还负责监督医学院和卫生系统。除了赠款资源外，该机构还提供了近1100万美元/vr的实物支持，成本分摊，试点和招聘计划的支持以及翻新费用，这与NIH的资金比例超过1：1。密歇根州的蓝十字蓝盾和辉瑞公司也在进行大规模投资。各部门还贡献了100多名全职教师的潜在努力，使MICHR可以授予试点研究，K- 12和新的“迷你K计划”的努力。这些总资源用于创建强大的基础设施和基于强大的现有单位和计划的支持，以及在关键的临床和翻译学科的学术课程，提供教师的领导，专业知识和咨询以及高质量的服务。这些课程包括生物医学信息学，生物统计学，临床翻译，新方法，技术核心，社区参与，伦理学，健康差异和监管支持。还描述了一个从根本上重新配置的参与者和临床互动资源。这些计划都是由一个教育计划，达到广泛的观众团结：从本科生到职业生涯中期的教师，从基础科学家到人口研究人员，从工作人员到社区成员。加速选项和强化计划都可用。最后，一个强大的试点计划将支付高达800万美元/年的试点资金，重点是刺激转化和跨学科研究。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The University of Michigan Clinical and Translational Sciences Award (UM CTSA) will focus the formidable strengths of one of the world's finest research institutions on supporting and facilitating clinical and translational "team science". The UM CTSA will be housed in the newly created Michigan Institute of Clinical and Health Research (MICHR). MICHR was created by the University to maximize the potential of an institution that is extremely supportive of interdisciplinary research and has tremendous strengths in the health sciences. MICHR creates a partnership between relevant unit of the University, the NIH, external industry partners, and the community. The overwhelming majority of UM schools, colleges, and institutes are participating, including the top-ranked Schools of Business, Dentistry, Medicine, Nursing, Social Work, and Public Health, the Colleges of Engineering, Pharmacy, and Literature, Science and Arts, the Division of Kinesiology, the Institute of Social Research, and the Life Sciences Institute. The University-owned Health System, which includes integrated outpatient and inpatient facilities, is contributing significantly to a strong partnership with the UM CTSA. The Director of MICHR is the PI of the UM CTSA grant, and reports to a University Executive Vice President, who also oversees the Medical School and Health System. In addition to the grant resources, the institution is contributing nearly $11 million/vr of in-kind support, cost-sharing, support of pilot and recruitment programs, and renovation costs, a more than 1:1 match of NIH dollars. Blue Cross Blue Shield of Michigan and Pfizer are also making sizable investments. Departments are also contributing more than 100 FTE in potential faculty effort, so that MICHR can grant effort for pilot studies, K- 12, and new "mini-K programs". These aggregate resources are used to create robust infrastructure and support based on strong existing units and programs, as well as academic programs in key clinical and translational disciplines, to provide faculty leadership, expertise, and consultation as well as high quality services. These Programs are in Biomedical Informatics, Biostatistics, Clinical Translation, Novel Methods, Technical Cores, Community Engagement, Ethics, Health Disparities, and Regulatory Support. A radically reconfigured Participant and Clinical Interactions Resource is also described. These programs are all united by an Education Program that reaches a wide spectrum of audiences: from undergraduates to mid-career faculty, from basic scientists to population researchers, from staff to community members. Both accelerated options and intensive programs are available. Finally, a robust pilot program will disburse up to $8 million/yr in pilot funds, focusing on stimulating translational and interdisciplinary studies.