Metathesis Reactions as the Basis for Construction of Aromatic Compounds: Application to Both Methodology and Synthesis

化学是一门充满活力的学科，是许多不同科学进步的中心。有机化学研究各种不同形式的碳的反应性，可以看作是发生在生物体内的化学反应。化学家们一直在寻找设计和构建分子的新方法（合成化学就是分子结构），而这一提议描述了一种使用新型催化剂制造有价值分子的简短而有力的新方法。该提议的核心分子是芳香族化合物，它们具有特殊性质，是大多数已知药物制剂的组成部分。因此，我们迫切需要有新颖、高效和强大的方法来制备新的芳香族化合物，以便我们对它们进行研究和利用。此外，新型催化剂的开发也很重要，因为它使化学反应进行得更快、更清洁、浪费更少：这显然对工业和环境都是一件好事。

Chemistry is a dynamic subject that is at the centre of many different scientific advances. Organic chemistry is concerned with the reactivity of carbon in all its different forms and can be viewed as the chemistry taking place within living things. Chemists are constantly looking for new ways of designing and building molecules (synthetic chemistry is molecular architecture) and this proposal describes a short and powerful new way of making valuable molecules using a new type of catalyst. The molecules at the heart of the proposal are aromatic compounds which have special properties and are the building blocks of most known pharmaceutical agents. Therefore, it is imperative that we have novel, efficient and powerful methods for making new aromatic compounds so that we can study and use them. In addition, the development of new catalysts is also important because it makes chemical reactions run faster, cleaner and with less waste: this is clearly a good thing for industry and also for the environment.