TAILORING BEHAVIORAL MANAGEMENT TO REARING AND RESEARCH

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 美国农业部关于非人类灵长类动物环境改善的政策草案已经制定，以提供更具体的指导方针，说明哪些措施足以满足圈养灵长类动物的心理需求，但需要研究来指导其实施。 该项目为杜兰国家灵长类动物研究中心的灵长类动物福利和管理提供了直接利益。 由于恒河猴在生物医学中的广泛应用以及需要加强对具有本项目所探讨背景的猴子的管理，因此正在对恒河猴进行研究。 重点放在社会群体和人类互动丰富。 利用行为、生理和临床数据，我们1）比较了连续完全接触、连续保护接触和间歇性完全接触对成对饲养恒河猴的影响，2）比较了几种数量和形式的人类/灵长类动物相互作用对单独饲养的两性个体行为健康的影响。 受试者来自以下人群：在社会环境中由母亲抚养的人，在没有其他社会伙伴的情况下由母亲抚养的人，以及由托儿所抚养的人，有些人在婴儿期有同伴接触，有些人没有同伴接触。 初步分析发现，1）连续和间歇性全接触对外壳都具有类似的行为益处，其中大部分在受保护接触中未观察到，以及2）非结构化相互作用和20分钟的混合效应。wk.的正强化训练，但只在养育类别涉及母亲养育。 例如，观察到焦虑相关行为和一些异常行为类别减少，但也观察到亲和行为减少和不活动增加。 在各种异常养育背景的受试者中没有检测到行为变化，也没有少量的训练。 该项目旨在为有关非人灵长类动物行为管理的不断变化的监管气候的决策提供科学依据。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The USDA Draft Policy on Environmental Enhancement for Nonhuman Primates has been developed to provide more specific guidelines as to what measures sufficiently address the psychological needs of captive primates, but research is needed to guide its implementation. This project is providing direct benefit to the primate well-being and management of the Tulane National Primate Research Center colony. Rhesus macaques are being studied due to their widespread use in biomedicine and the need for enhanced management of monkeys with the backgrounds to be explored in this project. Focus is placed on social grouping and human interaction as enrichment. Using behavioral, physiological, and clinical data, we are 1) comparing the effects of continuous full contact, continuous protected contact, and intermittent full contact for pair-housing rhesus macaques, and 2) comparing the effects of several quantities and forms of human/primate interaction on the behavioral well-being of singly-housed individuals of both sexes. Subjects are drawn from the following populations: those mother-reared in a social setting, those mother-reared without other social partners, and nursery-reared individuals, some with and some without peer contact in infancy. Preliminary analyses have found that 1) both continous and intermittent full contact pair housing confer similar behavioral benefits, most of which were not observed in protected contact, and 2) mixed effects of unstructured interaction and 20 min./wk. of positive reinforcement training were observed, but only among the rearing categories involving mother-rearing. For example, reductions in anxiety-related behaviors and some abnormal behavior categories were observed, but reduced affiliative behavior and increased inactivity was observed as well. No behavioral changes were detected among subjects with a variety of abnormal rearing backgrounds, nor with smaller amounts of training. This project aims to provide the scientific underpinning for decisions relating to the changing regulatory climate governing the behavioral management of non-human primates.