TAILORING BEHAVIORAL MANAGEMENT TO REARING AND RESEARCH

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 背景：美国农业部关于改善非人类灵长类动物环境的政策草案已经制定，以提供更具体的指导方针，说明哪些措施足以解决圈养灵长类动物的心理需求，但需要研究来指导其实施。该项目正在为杜兰国家灵长类研究中心群体的灵长类福祉和管理提供直接好处。由于恒河猴在生物医学中的广泛应用，以及需要加强对猴子的管理，因此正在对猕猴进行研究，这一背景将在本项目中探索。重点放在社会群体和人与人之间的互动作为财富。利用行为学、生理学和临床数据，我们1)比较了连续完全接触、连续保护接触和间歇性完全接触对配对恒河猴的影响，2)比较了几种数量和形式的人/灵长类互动对独居猕猴行为幸福感的影响。方法：研究对象来自以下人群：在社会环境中由母亲抚养的人，没有其他社会伙伴的母亲养育的人，以及托儿所抚养的人，其中一些人在婴儿时期有同伴接触，另一些人没有同伴接触。结果：初步分析发现，1)连续的和间歇性的完全接触对住房都具有类似的行为益处，并且不会导致伤害发生率的差异；在保护性接触中观察到的行为益处较少，并且没有差异；2)非结构化互动或积极强化训练的影响很小，尽管在那些表现出来自大型出生社交团体以外的养育环境并且在基线中表现出较高水平的受试者中，异常行为水平降低。结论：基于到目前为止的结果，该项目将为与管理非人类灵长类行为管理的不断变化的监管环境相关的决策提供科学基础。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Background: The USDA Draft Policy on Environmental Enhancement for Nonhuman Primates has been developed to provide more specific guidelines as to what measures sufficiently address the psychological needs of captive primates, but research is needed to guide its implementation. This project is providing direct benefit to the primate well-being and management of the Tulane National Primate Research Center colony. Rhesus macaques are being studied due to their widespread use in biomedicine and the need for enhanced management of monkeys with the backgrounds to be explored in this project. Focus is placed on social grouping and human interaction as enrichment. Using behavioral, physiological, and clinical data, we are 1) comparing the effects of continuous full contact, continuous protected contact, and intermittent full contact for pair-housing rhesus macaques, and 2) comparing the effects of several quantities and forms of human/primate interaction on the behavioral well-being of singly-housed individuals of both sexes. Methods: Subjects are drawn from the following populations: those mother-reared in a social setting, those mother-reared without other social partners, and nursery-reared individuals, some with and some without peer contact in infancy. Results: Preliminary analyses have found that 1) both continous and intermittent full contact pair housing confer similar behavioral benefits and do not result in differences in the incidence of wounding; fewer behavioral benefits and no differences in wounding were observed in protected contact, and 2) few effects of either unstructured interaction or positive reinforcement training have been observed, although reduction in levels of abnormal behavior among subjects that show derive from rearing settings other than large natal social groups and show high levels in baseline. Conclusion: Based on the results up to this point, this project will provide the scientific underpinning for decisions relating to the changing regulatory climate governing the behavioral management of non-human primates.