UCSD Cancer Center Training Program in Drug Development

描述（由申请人提供）：这是一个新的为期两年的博士后培训计划在癌症研究，更具体地说，在新的癌症药物的发展，在丽贝卡和约翰·摩尔UCSD癌症中心，NCI指定的综合癌症中心的应用。16名教师来自医学院的医学，病理学，外科学和药理学系以及Skaggs UCSD药学和药物科学学院。每个教师导师是癌症中心的参与成员，具有同行评审的癌症或癌症相关的研究资金。该计划很好地融入了癌症中心和UCSD的其他癌症相关活动。目标是在这个为期两年的项目中招募和维持8名MD和PhD科学家，从事学术癌症研究，重点是针对发展治疗学的转化研究。学员将被要求通过医学院管理和NIH资助的CREST计划参加课程;由该培训计划协调的系列讲座，癌症中心和部门研讨会，学员的期刊俱乐部，以及定期安排的会议，以扩大他们的癌症研究培训和观点。所有参与的教师正在进行转化研究，并已被选中，因为他们在新的癌症治疗的兴趣。该计划将采用相关的NCI赠款项目，包括U 56规划赠款癌症中心/少数民族机构合作计划在癌症的差距，以及一个悬而未决的U 54赠款申请学术公共，私人合作计划（AP 4）。它还将采用最近开放的摩尔癌症中心大楼，这是一个270，000平方英尺的最先进的多用途结构，将临床护理与基础和预防研究相结合。制定了方法，确保所有受训人员都得到关于负责任地进行研究和科学诚信原则的适当指导。 对癌症相关学术研究感兴趣并致力于至少两年研究培训的医学博士研究员将从UCSD以及全国范围内的血液学/肿瘤学，外科学和放射学奖学金计划中招募。博士申请人来自UCSD内部和其他研究型大学，在生物学，生物化学，化学和分子或细胞生物学方面有很强的背景，并选择发展与开发新的癌症疗法相关的技能。将通过我们的伙伴关系赠款和其他工具作出特别努力，为该计划招募和留住特殊的少数民族和妇女候选人。

DESCRIPTION (provided by applicant): This is an application for a new two-year postdoctoral training program in cancer research and more specifically in the development of new cancer agents, at the Rebecca and John Moores UCSD Cancer Center, an NCI designated comprehensive cancer center. The 16 faculty members come from the departments of Medicine, Pathology, Surgery, and Pharmacology within the medical school and the Skaggs UCSD School of Pharmacy and Pharmaceutical Sciences. Each faculty mentor is a participating member of the Cancer Center, having peer reviewed cancer or cancer-related research funding. This program is well integrated into the other cancer related activities of the Caner Center and of UCSD. The goal is to recruit and maintain 8 MD and PhD scientists in this two year program for careers in academic cancer research, with an emphasis on translational research targeted at developmental therapeutics. Trainees will be required to take courses through the medical school managed and NIH funded CREST program; a lecture series coordinated by this training program, Cancer Center and departmental seminars, a journal club for the trainees, and regularly scheduled conferences to expand their cancer research training and perspectives. All of the participating faculty are conducting translational research and have been selected because of their interest in new cancer therapeutics. This program will employ related NCI grant projects including a U56 planning grant for a cancer center/minority institution partnership program in cancer disparities, as well as a pending U54 grant application for an Academic Public, Private Partnership Program (AP4). It will also employ the recently opened Moores Cancer Center building, a 270,000 sf state of the art multi-use structure combining clinical care with basic and prevention research. Methods are in place to ensure that all trainees are properly instructed in the principles of responsible conduct of research and scientific integrity. MD fellows who are interested in academic research related to cancer, and committed to at least two years of research training will be recruited from the Hematology/Oncology, Surgery and Radiology fellowship programs here at UCSD as well as nationwide. PhD applicants come to us from within UCSD and from other research universities with strong backgrounds in biology, biochemistry, chemistry and molecular or cellular biology, and choose to develop their skills related to developing new cancer therapeutics. Special efforts will be made through our partnership grant and other vehicles to recruit and retain exceptional minority and women candidates to the program.