TRAINING GRANT ON THE BIOLOGY OF AGING

拟议的计划是一个为期5年的机构培训补助金在生物学的延续， 老龄问题，2003年由两个部门的培训赠款合并而成。我们要求资金， 资助10名博士后和6名博士后。美国即将到来的老年人雪崩 结合最近在理解衰老基本机制方面的重大进展， 大量的需求，研究人员培训，以调查手段，延迟和缓解疾病的 人口老龄化位于圣安东尼奥的得克萨斯大学健康科学中心是一项重要的研究， 研究机构在生物学的老化，目前收到更多的研究经费从生物学老化 计划的国家老龄化研究所（NIA）比任何其他独立的医疗机构。的 拟议的培训计划的主要目标是为研究生和 博士后研究员的职业生涯作为领导者在基础生物学研究的老龄化。培训计划 涉及25名教职员工（14名男性，11名女性），并利用 我们的内森休克中心提供的独特资源， 卓越的生物学老化和机构的承诺，并扩大资源， 巴肖普学院本身。学员将根据学术成就、他们的兴趣和兴趣进行竞争性选择。 以及从事研究的动机。每个学员的主要活动是 发展他们的教师监督的研究项目，这是因为合作的程度 在我们的教师中，往往会产生令人惊讶的团队指导。另一个关键组成部分是 需要在我们的两个衰老生物学课程中获得的衰老生物学方面的广泛知识， 学员可以把他们的研究放在适当的科学背景下。除了这种正式的说教之外， 培训，我们要求学员参加每周老化研究杂志俱乐部和Barshop研究所 系列研讨会。我们的计划还强调与多个场地进行科学交流的培训， 训练学员的书面及口头表达技巧。拟议培训计划的时间安排 是有利的，因为它将跨越我们的研究生课程的过渡，从其目前的地位， 衰老的特殊生物学跟踪细胞与结构生物学系内的未来地位， 一个独立的研究生项目--美国第一个衰老生物学博士项目。的 过渡进程已经启动，并将在拟议供资期间完成。

The proposed program represents a 5-year continuation of an institutional training grant in the biology of aging, which was consolidated in 2003 from two departmental training grants. We request funds to support 10 predoctoral and 6 postdoctoral trainees. The impending avalanche of elderly in the US combined with major recent advances in understanding fundamental mechanisms of aging has created a substantial demand for researchers trained to investigate means of delaying and relieving the ailments of an aging population. The University of Texas Health Science Center at San Antonio is a premier research institution in the biology of aging, currently receiving more research funding from the Biology of Aging Program of the National Institute on Aging (NIA)than any other stand-alone medical institution. The primary goal of the proposed Training Program is to intellectually prepare both graduate students and postdoctoral fellows for careers as leaders in basic biological research in aging. The Training Program involves 25 faculty members (14 men, 11 women) and takes advantage of the synergies created by intensely collaborative personnel, the unique resources available from our Nathan Shock Center of Excellence in the Biology of Aging and the institutional commitment to, and expanding resources of, the Barshop Institute itself. Trainees will be chosen competitively based on academic excellence, their interest in aging research, and motivation for careers in research. The main activity of each trainee is the development of their faculty-supervised research project, which because of the extent of collaboration among our faculty tends to result surprisingly often in team mentorships. Another key component is to require broad knowledge in the biology of aging acquired in our two biology of aging courses such that trainees'can place their research in an appropriate scientific context. In addition to this formal didactic training, we require trainees to attend the weekly Aging Research Journal Club and the Barshop Institute seminar series. Our program also emphasizes training in scientific communication with multiple venues for trainees to hone skills in both written and oral presentation. The timing of the proposed Training Program is propitious in that it will span the transition of our graduate student program from its current status as a Special Biology of Aging Track within the Department of Cellular & Structural Biology to its future status as an independent graduate program - the nation's first Ph.D.program in the Biology of Aging. That transition process has already been initiated and will be completed during the proposed funding period.