Vanderbilt-Zambia Network for Innovation in Global Health Technologies

描述（由申请人提供）：范德比尔特-赞比亚全球卫生技术创新网络（VZNIGHT）将在综合培训环境中确定和培养12名美国和赞比亚研究受训人员（4组，每组3人），以开发和部署新的低资源诊断技术，使赞比亚能够推进其疟疾控制运动。每个受训小组将在多学科环境中开发和实施自己独特的疟疾检测创新解决方案，其中包括范德比尔特大学和多个赞比亚伙伴机构的基础科学、工程科学以及全球卫生和临床科学，包括Macha疟疾研究所、赞比亚大学、国家疟疾控制中心和热带疾病研究中心。美国和赞比亚博士后研究人员的年度三方队列--基础科学、工程科学和临床或公共卫生科学各一名实习生--将被纳入范德比尔特现有的低资源技术开发团队一年，在此期间，他们将作为项目团队的多学科核心，各自做出贡献并反映他人的观点。为了将研究成果转化为实际产品，这些研究小组将在赞比亚进行为期六个月的实地测试，以验证其技术，在那里他们将评估新技术在寄生虫流行率高、中、低三个层次上的有效性。学员将有无数正式和非正式的学习机会，包括范德比尔特的全球健康课程的基础技能，一个特殊的VZNIGHT系列研讨会，广泛的课程选择审计，以补充他们的正式培训或拓宽他们的多学科视角，月刊俱乐部和研究审查，以及VU工程管理计划的创新战略顶点课程。我们还将在赞比亚和美国开展短期培训，包括在赞比亚为广泛的科学家举办项目初期和结束时的培训讲习班，内容涉及创新技术的实施和使用、研究伦理、赠款撰写和手稿撰写。我们还将把选定的赞比亚导师带到范德比尔特参加为期2-4周的研讨会，主题包括创新技术、工程管理、生物医学信息学和知识产权。VZNIGHT将建立一个创新网络，开发一个持续的技术和产品管道，提高诊断能力，并协助赞比亚卫生系统实现其无疟疾赞比亚的目标。通过将计划校友整合到赞比亚的多个机构（大学，农村卫生系统，卫生部），VZNIGHT开发的专业知识将在全国范围内，与范德比尔特科学家和未来的学员的联系将继续开发和实施新技术。包括知识产权和许可证在内的资产将为赞比亚带来长期利益。

DESCRIPTION (provided by applicant): The Vanderbilt-Zambia Network for Innovation in Global Health Technologies (VZNIGHT) will identify and nurture 12 American and Zambian research trainees (4 cohorts of 3) in an integrated training environment to develop and deploy new low-resource diagnostic technologies to enable Zambia to advance its malaria control campaign. Each trainee team will develop and implement its own unique innovative solution for malaria detection in a multidisciplinary environment that includes the basic sciences, engineering sciences, and global health and clinical sciences at Vanderbilt University and multiple Zambia partner institutions, including the Malaria Institute at Macha, the University of Zambia, the National Malaria Control Centre, and the Tropical Diseases Research Centre. Annual tripartite cohorts of US and Zambian postdoctoral researchers - one trainee each from the basic sciences, engineering sciences, and clinical or public health sciences - will be integrated into Vanderbilt's existing low-resource technology development team for a year, during which they will function as the multidisciplinary core of the project team, each contributin and reflecting on the others' perspectives. To effect the translation of research findings into realized products, the cohorts will then validate their technologies in field tests for six months n Zambia, where they will evaluate the effectiveness of the new technologies across the three strata of parasite prevalence - high, medium, and low. Trainees will have myriad formal and informal learning opportunities, including Vanderbilt's Foundational Skills in Global Health course, a special VZNIGHT seminar series, audits of a wide selection of courses to complement their formal training or broaden their multidisciplinary perspective, monthly journal club and research review, and the VU Engineering Management Program's Innovation Strategy Capstone course. We will also conduct short-term trainings in Zambia and the US, including early- and end-of-program training workshops in Zambia for a broad range of scientists on implementation and use of innovative technologies, ethics in research, grant writing, and manuscript writing. We will also bring selected Zambian mentors to Vanderbilt for workshops of 2-4-weeks' duration on topics such as innovative technologies, engineering management, biomedical informatics, and intellectual property. VZNIGHT will establish a network for innovation that develops an ongoing pipeline of technologies and products that improve diagnostic capabilities and assist the Zambian health system to realize its goal of a malaria-free Zambia. By integrating program alumni into multiple Zambia-based institutions (university, rural health systems, Ministry of Health), the expertise developed by VZNIGHT will have a nationwide scope, and linkages to Vanderbilt scientists and future trainees will continue to develop and implement new technologies. Assets including intellectual property rights and licenses will secure long-term benefits to Zambia.