Duke University Program in Environmental Health

描述(由申请人提供) 杜克大学环境健康计划(UPEH)是一项拟议的博士前培训计划，将为学生在环境健康方面的研究生涯做好准备。UPEH是一个跨部门、多学科的项目，博士学位由该部门和该项目联合授予。培训包括1)核心领域的课堂教学(药理学、环境毒理学或哺乳动物毒理学、环境健康)和适合学生研究的量化方法，包括统计学、毒理学和环境健康的重点主题；2)研讨会和专题讨论会，包括文献分析和主要研究的陈述；3)负责任的研究行为的入门和持续指导；4)实验室研究。 杜克大学在环境健康方面的研究优势包括：1)人类环境健康与疾病，在心肺健康与疾病、发育与儿童健康、神经健康与疾病、癌症与环境以及全球健康方面具有独特优势；2)接触科学，侧重于内分泌干扰物、药物、碳氢化合物和阻燃剂、纳米材料以及包括痕量金属和金属在内的无机污染物；3)环境毒理学，侧重于阐明毒素和其他环境对人类健康影响的分子作用机制。 由杜克大学医学中心、尼古拉斯环境学院、普拉特工程学院和三一艺术与科学学院支持的卓越研究环境为核心教育环境提供了实验室和共享设施，为学生提供前沿研究方法方面的培训。 杜克大学的核心教员担任博士前学生的主要顾问。该计划进一步丰富了来自研究三角园区机构的兼职教师，如NIEHS、美国环保局和哈姆纳健康研究所，以及其他三角大学(北卡罗来纳中央大学、北卡罗来纳州立大学和北卡罗来纳大学教堂山分校)。这些教职员工提供研讨会、讲座、学生委员会成员，并提供技术专长、研究设施和职业指导。UPEH的成功将取决于调查人员吸引优秀学生加入该项目的能力。UPEH的前身(综合毒理学和环境健康项目)的招聘和录取工作一直为他们提供了渴望从事环境健康和相关分学科职业生涯的优秀实习生。这一招募努力包括各种积极的战略，以招募代表人数不足的少数群体。 公共卫生相关性：杜克大学的UPEH将为博士前研究员提供课堂和实验室培训，为他们在环境健康研究中担任领导角色做好准备。环境因素有助于人类疾病的病因学，包括哮喘、癌症和生殖障碍。该项目的受训人员将有助于我们理解环境暴露于化学品和其他应激源之间的联系，潜在的细胞反应机制，以及人类健康结果。

DESCRIPTION (provided by applicant) The Duke University Program in Environmental Health (UPEH) is a proposed predoctoral training program which will prepare students for research careers in environmental health. The UPEH is an interdepartmental, multidisciplinary program in which Ph.D. degrees are awarded jointly by the Department and the Program. Training includes 1) classroom instruction in core areas (Essentials of Pharmacology, Environmental Toxicology or Mammalian Toxicology, Environmental Health), and quantitative approaches appropriate for student research including Statistics, Focused Topics in Toxicology and Environmental Health; 2) Seminars and symposia that include literature analysis and presentation of primary research; 3) Introductory and ongoing instruction in Responsible Conduct of Research; 4) Laboratory research. Research strengths in environmental health at Duke University include: 1) Human environmental health and disease with specific strengths in cardiopulmonary health and disease, development and children's health, neurological health and disease, cancer and the environment, and global health; 2) Exposure science with a focus on endocrine disrupters, pharmaceuticals, hydrocarbons and flame retardants, nanomaterial's and inorganic pollutants including trace metals and metalloids, and 3) Environmental toxicology, focused on elucidating molecular mechanisms of action for toxins and other environmental influences on human health. The outstanding research environment supported by Duke's Medical Center, the Nicholas School of the Environment, Pratt School of Engineering, and Trinity College of Arts and Sciences provides the core educational environment with laboratories and shared facilities supplying training in leading-edge approaches to the students' research. Core Duke faculty members in the UPEH serve as primary advisors for pre-doctoral students. The Program is further enriched by adjunct faculty from the Research Triangle Park-based institutions such as NIEHS, US EPA, and Hamner Institute for Health Research, and other triangle universities (North Carolina Central University, NC State University, and UNC Chapel Hill). These faculty members provide seminars, lectures, serve on student committees, and provide technical expertise, research facilities and career guidance. The success of the UPEH will depend on the investigators ability to attract excellent students into the Program. The recruiting and admissions efforts with the UPEH's predecessor (Integrated Toxicology and Environmental Health Program) have consistently provided them with outstanding trainees who are eager to embark upon careers in environmental health and related sub-disciplines. This recruiting effort includes a variety of active strategies to recruit underrepresented minorities. Public Health Relevance: Duke's UPEH will provide pre-doctoral fellows with classroom and laboratory training which will prepare them for leadership roles in research in environmental health. Environmental factors contribute to the etiology of human disease including asthma, cancer and reproductive disorders. Trainees in this program will contribute to our understanding of the linkages among environmental exposures to chemicals and other stressors, mechanisms underlying cellular responses, and human health outcomes.