Tulane University Training Program for Diversity in tRanslation and Implementation research in cardioVascular disEase (DRIVE)

项目摘要/摘要：尽管在确定风险因素和使用循证方法方面取得了进展 管理心血管疾病的战略，最近死亡率的下降已经停滞不前，而且种族/民族 差距是持久的。总体而言，从事简历研究职业的种族和少数民族人数 是低的。翻译研究是一个快速发展的领域，它将产生于 实验室、临床或人群研究临床应用，而实施研究促进 将研究结果和循证干预措施纳入医疗保健政策、公共卫生和 临床环境。训练有素、多样化的翻译和实施科学家队伍，他们可以测试 路易斯安那州迫切需要创新的想法以及推进已证明有效的疗法的采用和实践 以及密西西比三角洲地区，那里的CV健康指标往往是全国最差的 种族、社会经济地位和地理位置的差异是有据可查的。这样做的总体目标是 申请杜兰大学新的博士前T32培训计划是为了增加 来自代表性不足背景的翻译和实施研究人员，以建立多样化的员工队伍 这可以解决该地区的个人简历健康差距问题。年杜兰大学多样性培训计划 心血管疾病的翻译和实施研究(DRIVE)将借鉴 优秀的调查人员为来自代表性不足背景的实习生提供教学， 他们需要的经验、技能、指导和资源，才能成为简历翻译和 实施科学。该计划将为八名博士后提供深入、有组织的培训支持 来自不同背景和服务不足的候选人，利用杰出的调查人员和 CV临床试验中的转化性研究(T3)和基于社区的实施研究(T4)。推进器 培训计划将植根于多学科团队科学，整合初级和高级导师以 通过他们的个性化发展计划指导学员获得关键技能并应用这些技能 在实践研究中的经验，以解决路易斯安那州和密西西比河三角洲地区的简历健康差异 区域。项目主任将由一个执行运营委员会和一个外部委员会协助 顾问来自代表性不足的背景，拥有非凡的研究生涯和指导经验。 导师将使用明确和经过验证的方法来促进学员的发展和成功，同时 所有受训人员将参加一系列讲授基金写作、手稿写作和专业知识的工作坊。 发展技能，包括最佳实践战略，以优化演示、沟通和 网络。拟议的培训方案旨在促进翻译和翻译的多样化 实施劳动力，减少心血管疾病和代谢风险因素的负担，消除健康 路易斯安那州和全国的差距和改善卫生公平。

Project Summary/Abstract: Despite advances in the identification of risk factors and use of evidence-based strategies to manage cardiovascular (CV) diseases, recent declines in mortality have stalled and race/ethnic disparities endure. Overall, the number of racial and ethnic minorities who are engaged in CV research careers is low. Translation research is a rapidly evolving field which transforms scientific discoveries arising from laboratory, clinical, or population studies into clinical applications, while implementation research promotes the integration of research findings and evidence-based interventions into healthcare policy, public health and clinical settings. A well-trained and diverse workforce of translation and implementation scientists who can test innovative ideas and advance the adoption and practice of proven therapies are sorely needed in Louisiana and the Mississippi Delta region, where CV health indicators are often poorest in the nation and health disparities by race, socioeconomic status and geography are well documented. The overall objective of this application for a new predoctoral T32 training program at Tulane University is to increase the number of translation and implementation researchers from underrepresented backgrounds to build a diverse workforce that can tackle CV health disparities in the region. The Tulane University training program for Diversity in tRanslation and Implementation research in cardioVascular disEase (DRIVE) will draw on the expertise of outstanding investigators to provide trainees from underrepresented backgrounds with the didactics, experience, skills, mentoring and resources they need to become successful researchers in CV translation and implementation sciences. The program will provide in-depth, structured training support for eight predoctoral candidates from diverse and underserved backgrounds, leveraging outstanding investigators and on-going translational research in CV clinical trials (T3) and community-based implementation studies (T4). The DRIVE training program will be rooted in multidisciplinary team science with integration of junior and senior mentors to guide the trainee via their Individualized Development Plan in acquiring critical skills and applying these skills in hands-on research experiences to address CV health disparities across Louisiana and the Mississippi Delta region. The program director will be assisted by an executive operating committee and a committee of external advisors from underrepresented backgrounds with exceptional research careers and experience in mentoring. Mentors will use defined and proven methods to enhance the development and success of the trainees, while all trainees will participate in a series of workshops that teach grant writing, manuscript writing and professional development skills, including best practice strategies to optimize presentations, communications and networking. The proposed training program seeks to contribute to diversifying the translation and implementation workforce, reducing the burden of CV diseases and metabolic risk factors, eliminating health disparities, and improving health equity in Louisiana and the nation.