Overall Career Development

职业发展和培训计划 在上一次资助期间，人力资源教育中心设立了三个个人职业发展方案( MRCE临床和转译研究奖学金奖，MRCE生物安全奖学金计划， 和MRCE生物防御兽医奖学金)，以及两个小组培训计划(MRCE生物安全 课程和MRCE研讨会系列)。临床和转译研究奖学金计划是 旨在满足第七区和全国的需要，以增加执行任务的内科科学家队伍 高质量的生物防御和新发传染病研究。生物防御兽医 培训计划旨在满足第七区和全国对兽医科学家的需求 能够对能够领导比较医学的选定代理人、兽医进行高质量的研究 与特定代理人打交道的计划，以及可以培训其他兽医安全工作的兽医 A-C级特工。MRCE生物安全奖学金计划是生物安全方面的博士后奖学金 创建的目的是为国家生物防御研究工作提供一支能够建立 并监督学术界、工业界和政府的生物安全项目。它与 生物安全课程，该课程在BSL3提供了处理特定制剂的教学和实践培训 控制级别。最后，MRCE研讨会系列支持来自以下国家的领先科学家的研究演讲 第七区域以外的生物防御和新发传染病研究的前沿科学。 作为竞争性更新进程的一部分，指导委员会审查了MRCE的所有职业 发展和培训方案、区域内以及区域和国家内的其他培训机会 人力需求。我们得出了以下结论： ？三个MRCE职业发展方案总体上都成功地达到了各自的专业要求 目标(见部分)，但有人担心，支助期限(1年)不足以 真正促进临床和转化性研究奖学金的职业发展 计划或兽医培训计划。 ？在目前的资助环境下，高级博士后研究员和初级博士后研究员越来越难 对生物防御或新发传染病研究感兴趣的教师可获得资助 需要导师帮助他们成为独立的调查人员。 选择为生物防御的临床或转化性研究进行培训的医生仍然短缺 和新发传染病。我们需要制定计划，招募这些人加入 菲尔德。？ 如果我们要扩大对生物防御和新出现的传染病感兴趣的科学家的管道 通过研究，我们需要探索在个人职业生涯的早期阶段瞄准个人的有效性。vt.给出 在目前的筹资环境下，津贴支持可能是一个有吸引力的机制 选拔研究生从事生物防御和新发传染病研究。是这样的 一个项目也将使他们的导师受益，并扩大MRCE支持的调查员队伍。 第七区的独特之处之一是有三所强大的兽医学校 (例如密苏里大学、堪萨斯州立大学、爱荷华州立大学)。仍然有一个关键的 需要为生物防御努力培训更多的DVM。他们将在直接研究中发挥关键作用 选择药物，开发大小动物疾病模型，并在监督设施中 在那里，动物被用于生物防御研究。这将成为新的更大的需求 区域(RBL)和国家(NBL)生物遏制实验室计划。 ？持续需要教授调查人员、博士后研究员、研究生、技术人员、 以及任何其他实验室人员如何安全地使用选定的试剂，特别是那些需要 BSL2和BSL3围堵。我们预计申请与我们合作的个人将继续增加 这些代理人，以及对这项工作所涉及的监管和安全问题缺乏了解 对科学家来说可能是一个重大的障碍。MRCE提供了一个独特的机会来开发正式、 为我们地区提供一致的培训计划。 随着RBL和NBL设施的上线，区域和国家的需求将会增加 适用于有能力建立和监督生物安全计划的个人。这绝对是 增加参与生物防御研究工作的机构数量。我们应该继续我们的 计划“培训培训员”，以满足这一需求。 仍然需要加强关于生物防御和新出现的传染病的教育 在我们区域内进行研究。一系列研讨会，以来自这一领域的领导者的前沿研究为特色 现场提供教育益处，可以促进协作，并提供一个促进MRCE的论坛 计划和资源。 基于这一评估，MRCE建议继续其三个人的职业发展 计划，以及两个团体职业发展活动。我们详细描述了这些项目中的每一个 后续章节。因为我们对临床和转化性研究进行了重大修改 奖学金计划，将支持期限增加到3年，并开放资格要求 包括初级讲师或早期助理教授阶段，我们现在称之为MRCE职业生涯 生物防御和新发传染病研究发展奖。

Career Development and Training Programs During the previous funding period the MRCE established three individual career development programs (the MRCE Clinical and Translational Research Fellowship Award, the MRCE Biosafety Fellowship Program, and the MRCE Biodefense Veterinary Fellowship), and two group training programs (the MRCE Biosafety Course and the MRCE Seminar Series). The Clinical and Translational Research Fellowship Program was designed to meet the needs of Region VII and the nation to increase the pool of physician-scientists performing high quality research on biodefense and emerging infectious diseases. The Biodefense Veterinary Medicine Training Program was designed to meet the needs of Region VII and the nation for veterinarian scientists that can perform high quality research on select agents, veterinarians that can lead comparative medicine programs that deal with select agents, and veterinarians that can train other veterinarians to safely work with class A-C agents. The MRCE Biosafety Fellowship Program was a post-doctoral fellowship in Biosafety created to provide the national biodefense research effort with a cadre of individuals capable of establishing and supervising biosafety programs in academia, industry, and government. It was associated with the Biosafety Course, which provided both didactic and hands-on training in handling select agents at the BSL3 containment level. Finally, the MRCE Seminar Series supported research talks from leading scientists from outside Region VII on cutting edge science in biodefense and emerging infectious diseases research. As part of the competitive renewal process, the Steering Committee reviewed all of the MRCE career development and training programs, other training opportunities within the region, and regional and national manpower needs. We reached the following conclusions: ¿ The three MRCE career development programs had generally been successful in meeting their major goals (see section ), but there was a concern that the duration of support (1 year) was not adequate to truly facilitate career development for either the Clinical and Translational Research Fellowship Program or the Veterinary Medicine Training Program. ¿ In the current funding environment it is increasingly difficult for senior post-doctoral fellows and junior faculty interested in biodefense or emerging infectious diseases research to obtain the grant support and mentorship needed to help them become independent investigators. ¿ There remains a shortage of physicians opting to train for clinical or translational research in biodefense and emerging infectious diseases. We need to develop programs to recruit these individuals into the field. ¿ ¿ If we are to expand the pipeline of scientists interested in biodefense and emerging infectious diseases research, we need to explore the efficacy of targeting individuals at earlier levels in their careers. Given the current funding environment, stipend support might be an attractive mechanism to introduce selected graduate students to research in biodefense and emerging infectious diseases research. Such a program would also benefit their mentors, and expand the pool of MRCE supported investigators. ¿ One of the unique aspects of Region VII is the presence of three strong schools of Veterinary Medicine (e.g. University of Missouri, Kansas State University, Iowa State University). There remains a critical need to train more DVMs for the effort in biodefense. They will play key roles in direct research on select agents, in developing large and small animal models of disease, and in supervising facilities where animals are used for biodefense research. This will become an even greater need with the new Regional (RBL) and National (NBL) Biocontainment Laboratory programs. ¿ There is an ongoing need to teach investigators, post-doctoral fellows, graduate students, technicians, and any other laboratory personnel how to safely work with select agents, especially those that require BSL2 and BSL3 containment. We anticipate a continued increase in individuals applying to work with these agents, and the lack of knowledge about the regulatory and safety issues involved in this work can be a significant barrier to scientists. The MRCE provides a unique opportunity to develop a formal, consistent training program for our region. ¿ As the RBL and NBL facilities come on line, there will be an increasing regional and national demand for individuals capable of establishing and supervising biosafety programs. This is absolutely key to increasing the number of institutions involved in the biodefense research effort. We should continue our program to "train the trainers" to meet this need. ¿ There remains a need for increased education about biodefense and emerging infectious diseases research within our region. A seminar series that features cutting edge research from the leaders in this field provides educational benefits, can spur collaborations, and provides a forum to promote MRCE programs and resources. Based on this assessment, the MRCE proposes to continue its three individual career development programs, and two group career development activities. We describe each of these projects in detail in the subsequent sections. Because we made significant modifications to the Clinical and Translational Research Fellowship program, increasing the duration of support to 3 years, and opening the eligibility requirements to include junior faculty at the instructor or early assistant professor stage, we now call it the MRCE Career Development Award in Biodefense and Emerging Infectious Diseases Research.