Modulating immune responses by targeting dendritic cells using dendritic cell specific markers.

调节免疫反应的能力将对健康有重大益处。树突状细胞（DC）是免疫系统的关键调节因子。不同类型的DC具有不同的细胞表面分子，并具有不同的调节功能。我们已经确定了四种新的DC表面分子，可用于靶向不同类型的DC。我们的目标是使用针对这些分子的抗体来增强疫苗的有效性或抑制自身免疫性疾病。

The ability to modulate immune responses would have major health benefits. Dendritic cells (DC) are key regulators of the immune system. Different types of DC possess different cell surface molecules and have differing regulatory functions. We have identified four novel DC surface molecules that can be used to target different types of DC. We aim to use antibodies against these molecules to either enhance the effectiveness of vaccines or to suppress autoimmune diseases.