Core Grant for Vision Research

描述(由申请者提供)：建议设立核心中心助学金，以支持德克萨斯大学西南医学中心的视觉研究。我们校园最近扩大的视觉研究为加强德克萨斯大学西南医学中心的视觉科学研究创造了一个机会，通过创建一个视觉研究核心设施，将促进和扩大目前由10个R0L奖授予9个PI的研究活动。德州大学西南医学中心由NEI支持的大多数研究活动共享三项主要技术：1)组织培养/克隆抗体生产；2)成像；以及3)生物化学/蛋白质纯化。在过去的几年里，眼科的研究人员分享了资源、技术专长和设备，以促进他们各自的研究计划在显著的合作气氛中。眼科实验室设施的扩展和为我们校园的研究人员获得额外的NEI补助金促使我们筹集了一笔核心补助金，作为加强这些研究活动的手段。建立核心设施将避免PI在眼科、精神科、发育生物学、生理学和神经科学系的基础技术重复。

DESCRIPTION (provided by applicant): A Core Center Grant is proposed to suppport vision research at The University of Texas Southwestern Medical Center. The recent expansion of vision research on our campus has created an opportunity to enhance visual science research at U.T. Southwestern Medical Center through the creation of a Vision Research Core Facility that will facilitate and expand the research activities that are currently supported by 10 R0l's awarded to 9 Pi's. The majority of NEI-supported research activities at U.T. Southwestern Medical Center share a common reliance on three major technologies: 1) tissue culture/monoclonal antibody production; 2) imaging; and 3) biochemistry/protein purification. Over the past several years, investigators in the Department of Ophthalmology have shared resources, technical expertise, and equipment to facilitate their respective research programs in a remarkably collegial atmosphere. The expansion of the Department of Ophthalmology's laboratory facilities and the acquisition of additional NEI grant support to investigators on our campus prompted us to assemble a core grant as a means of enhancing these research activities. Establishing core facilities would obviate duplication of fundamental technologies by PI's in the Departments of Ophthalmology, Psychiatry, Developmental Biology, Physiology, and Neuroscience.