ISU Vet-LIRN Infrastructure Grant Proposal

项目摘要 拟议的工作是爱荷华州立大学兽医之间的合作协议 诊断实验室(ISU VDL)和FDA兽药兽医中心 在以下方面提供支持： 1)参加FDA/Vet-LIRN批准的化学污染物样品分析； 2)提供分析数据，以支持潜在的监管用途；以及 3)参与其他项目，如小规模方法开发、方法 化学污染物分析的验证和矩阵扩展。 这些活动旨在支持FDA加强兽医协调 诊断实验室在加强国家食品安全系统方面的努力。 ISU VDL是由AAVLD提供切割的全方位服务完全认可的实验室 为爱荷华州及其他地区提供EDGE诊断服务。ISU VDL的案件装载量为 在美国是独一无二的，因为它主要是与食用动物有关的。爱荷华州是主要的食物 畜牧业生产状况。实验室不仅是食品领域的第一道防线 为全国各地的食用动物生产者提供安全保障，但也在大力保护 宠物动物健康。该项目将专门解决与化学污染有关的问题。 导致动物疾病或死亡。我们有大量来自爱荷华州的食用动物产品 出口到对食品安全敏感的欧盟和亚洲市场。 参与这一合作协议计划将不仅使FDA受益，也将使实验室受益 以及爱荷华州，因为这个项目的所有方面都为我们的产品增加了价值- 也就是说，准确和及时地分析检测结果，以保护动物和人类健康 化学污染物。 ISU VDL装备齐全，人员配备齐全，能够积极影响FDA的需求 在美国之音。具体地说，我们拥有必要的基础设施来支持培训、参与 质量保证过程和熟练程度测试，并共享数据以支持国家能力 发展。我们将快速准确地检测诊断样本，以协助FDA在 调查。作为粮食紧急反应的成员和长期参与者 作为Vet-LIRN的创始成员，我们已经证明了我们 拥有准确、高效地报告结果的基础设施。我们的工作质量 产品由一个独立的质量保证部门监督。总而言之，我们有 资源和基础设施，以及时交付我们的工作成果。我们已经准备好了 如果申请成功，与FDA就这笔拨款进行合作。

Project Summary The proposed work is for a cooperative agreement between Iowa State University Veterinary Diagnostic Laboratory (ISU VDL) and the FDA Center for Veterinary Medicine Vet-LIRN to provide support in the following areas: 1) To participate in FDA/Vet-LIRN sanctioned sample analysis for chemical contaminants; 2) To provide analytical data to support potential regulatory use; and 3) To participate in additional projects such as small scale methods development, method validation and matrix extension for analysis of chemical contaminants. These activities are designed to support the FDA in strengthening coordination of veterinary diagnostic laboratory efforts in enhancing the national food safety system. The ISU VDL is a full service fully accredited laboratory by the AAVLD which provides cutting edge diagnostic services to the State of Iowa and beyond. The case load at the ISU VDL is unique in the nation because it is predominantly food-animal related. Iowa is a major food animal producing state. The laboratory is not only the first line of defense in the area of food safety to food animal producers across the country, but is also heavily engaged in protection of pet animal health. This project will specifically address issues related to chemical contamination leading to animal illnesses or death. A significant amount of our food animal products from Iowa are exported overseas to the EU and Asia, markets that are sensitive to food safety. Participation in this cooperative agreement program will not only benefit the FDA, but the lab and the State of Iowa as well because all aspects of this project add value to our product- namely, accurate and timely analysis of test results to protect animal and human health from chemical contaminants. The ISU VDL is well equipped and staffed to positively impact the needs of the FDA as outlined in the FOA. Specifically, we have the necessary infrastructure to support training, participate in quality assuarance processes and proficiency tests, and share data to support national capacity development. We will quickly and accurately test diagnostic samples to assist the FDA in case investigations. As members and long-term participants in the Food Emergency Response Network (FERN) and also as founding members of Vet-LIRN, we have demonstrated that we have the infrastructure to report out results accurately and efficiently. The quality of our work product is overseen by an independent Quality Assurance Unit. In summary, we have the resources and infrastructure to deliver our work product in a timely manner. We are ready to collaborate with the FDA on this grant if the application is successful.