5P42ES027706 Sources, Transport, Exposure, and Effects of PFASs (STEEP) SRP

随着世界范围内对新出现的持久性污染物Per-2的日益关注， 和多氟烷基物质(PFAS)显然需要负担得起和可靠的 侦测工具。作为我作为陡峭超级基金中心实习生进行的研究的一部分，我 我正在验证一种新型的管被动采样器，该采样器将用于测量PFAS 地表水和地下水中的污染。目前的工作重点是验证 全氟辛烷磺酸在各种环境条件下的吸收，如流量、水温和是否存在 使用填充有商业吸着剂的微孔聚乙烯管的生物污垢 用作全氟辛烷磺酸的接收阶段。虽然目前的吸附剂通常用于PFAS 萃取剂是一种用于PFAS修复的新型环糊精吸附剂，它可以有更高的 对更大范围的全氟辛烷磺酸的吸附，从而改善了全氟辛烷磺酸在该管壁中的吸收 被动取样器。为了测试这一点，我建议去生产这一产品的私人公司旅行。 环糊精吸附剂，Cyclopure Inc.in Skokie IL，以验证提取两者的方法 来自我的被动采样器的原生和大量标记的替代化合物，加载了他们的 吸着剂。Cyclopure Inc.是一家在SRP资助的赠款(R43ES029401)下工作的公司，他们的小说 被称为DEXSORB+的吸附剂是为了在可重复使用的情况下修复全氟辛烷磺酸而创建的。这 新型脱硫剂也比目前使用的脱硫剂更实惠，价格约为目前的20倍 每50克脱硫剂的脱硫率更低。除了验证更大范围内的提取方法之外 比我目前在罗德岛大学的实验室提供的PFAS标准更高，我将 在分析自己的Cyclopure液体样品时获得直接指导 色谱仪/质谱仪。在我的网站上有限地访问这台仪器 在大学期间，我将有宝贵的时间学习操作、故障排除和数据分析 Cyclopure Inc.的Matt Notter和Frank Cassou的指导。通过这次经历，我将 获得学习私营部门公司感兴趣的技能的独特机会 在我博士毕业之前。使用被动采样器跟踪协作 在州和联邦机构工作会让我广泛地接触到我将 当我完成学业时，请考虑一下。这一外部任务的预期结果将是一个改善 用于地表水和地下水中全氟辛烷磺酸的被动式采样器的设计将是负担得起的， 可重复使用，并且对所有利益相关者都是可靠的。这些结果将在SRP年度会议上分享 在外舰完成后的会议，这将允许广泛的 将向利益攸关方介绍这一潜在的PFAS测量工具。

With worldwide concern growing over the emerging persistent contaminates known as Per- and poly-fluorinated alkyl substances (PFAS) there is a distinct need for affordable and reliable detection tools. As part of my ongoing research as a trainee of the STEEP Superfund Center, I am in the process of validating a novel tube passive sampler that will be used to measure PFAS contamination in surface and ground waters. Current work has focused on validating the uptake of PFAS across environmental conditions like flow, water temperature, and presence of biofouling using a microporous polyethylene tube filled with a commercially available sorbent used as the receiving phase for PFAS. While the current sorbent is commonly used for PFAS extraction, a novel cyclodextrin sorbent designed for PFAS remediation, could boast higher sorption for a wider range of PFAS, thus improving uptake of PFAS within the walls of this tube passive sampler. To test this, I propose travelling to the private company that produces this cyclodextrin sorbent, Cyclopure Inc. in Skokie IL, to validate a method for extraction of both native and mass labeled surrogate compounds from my passive samplers, loaded with their sorbent. Cyclopure Inc. is a working under an SRP-funded grant (R43ES029401), and their novel sorbent called DEXSORB+, was created for remediation of PFAS while being re-useable. This novel sorbent is also more affordable than the currently used sorbent, costing about 20 times less per 50 grams of sorbent. In addition to validating an extraction method for a wider range of PFAS standards than available in my current laboratory at the University of Rhode Island, I will gain direct mentorship while analyzing my own samples on Cyclopure’s Liquid Chromatograph/Mass Spectrometry instrument. With limited access to this instrument at my university, I will have valuable time to learn operation, troubleshooting, and data analysis under the guidance of Matt Notter and Frank Cassou of Cyclopure Inc. Through this experience, I will get the unique opportunity to learn about the skills that interests private sector companies before graduating from my doctoral program. Follow up collaborations using passive samplers with state and federal agencies will give me broad exposure to many career paths that I will consider as I finish my studies. The expected outcome of this externship will be an improved design for a passive sampler for PFAS in surface and ground waters that will be affordable, reusable, and reliable for all stakeholders. These results will be shared at the SRP annual meeting following the completion of the externship, which will allow for a wide variety of stakeholders to be introduced to this potential tool for PFAS measurements.