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Anakinra for neutrophilic pustular skin disease

Anakinra for neutrophilic pustular skin disease
阿那白滞素（Anakinra）治疗中性粒细胞性脓疱性皮肤病
批准号：
10014724
负责人：
Edward Cowen
金额：
$14.9万
依托单位：
DIVISION OF BASIC SCIENCES - NCI
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/10014724
关键词：
BiologicalClinicalCollaborationsDiseaseEnrollmentGoalsInterleukin-1LaboratoriesOutcomePET/CT scanPathway interactionsPatientsProtocols documentationPustular psoriasisSamplingSerumTherapeuticTissuesTreatment Protocolsanakinracardiovascular disorder riskdesignneutrophilskin disorder

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中文摘要
翻译
到目前为止，已有17名患者参加了这一治疗方案。已经确定了25-30名患者的目标，以确定阿纳金纳是否对脓疱性中性粒细胞皮肤病有效。除了临床结果，组织和血清样本正被送往Raphaela Goldbach-Mansky、Maria Morasso、Alison McBride和Nehal Mehta的实验室，以进一步调查导致脓疱性牛皮癣的生物途径，包括PET/CT评估的心血管疾病风险。
英文摘要
To date, 17 patients have enrolled on this treatment protocol. A goal of 25-30 patients has been established to determine if anakinra has efficacy for pustular neutrophilic skin disease. In addition to the clinical outcomes, tissue and serum samples are being sent to the lab of Raphaela Goldbach-Mansky, Maria Morasso, Alison McBride, and Nehal Mehta in order to further investigate the biologic pathways responsible for pustular psoriasis, including risk of cardiovascular disease as assessed by PET/CT.
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Anakinra for neutrophilic pustular skin disease
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海外基金
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