MRI cardiovascular catheterization technology development

在过去的一年里，我们继续使用0.55T的新型低场高性能磁共振成像系统进行人体心血管磁共振成像。该系统以较低的SAR保存成像，从而允许使用导电金属心血管导丝进行MRI插管。这允许使用基本的金属导管工具，而不会有危险的加热。 与阿德里安·坎贝尔-沃什伯恩的实验室合作，我们正在帮助描述低场下感兴趣组织的基本磁共振特性。 我们研究了低场高性能MRI成像铁敏感标记用于导丝跟踪和导航的价值。 在人类研究对象中，我们研究了低场高性能磁共振成像对减轻不可挽回地扭曲心电复极的磁流体效应的影响。 我们正在与业界密切合作，通过合作研究和开发协议，在介入MRI实验期间以及在X射线和MRI之间传输期间，安全地监测和记录患者的血流动力学。我们正在与业界密切合作，将我们的开发转化为可广泛用于世界各地医疗保健的商业工具。 具体地说，我们正在研究确保实时核磁共振期间导电金属导管设备的安全性的方法。

During the past year we continued human cardiovascular MRI using a novel low-field and high-performance MRI system at 0.55T. The system preserves imaging with reduced SAR which allows MRI catheterization using conductive metallic cardiovascular guidewires. These allow using fundamental metallic catheter tools without dangerous heating. In collaboration with the laboratory of Adrienne Campbell-Washburn we are helping to characterize fundamental MR properties of tissues of interest at low field. We have investigated the value of low-field high-performance MRI to image iron susceptibility markers for guidewire tracking and navigation. We have investigated the impact of low-field high-performance MRI to mitigate the magnetohydrodynamic effect that irrevocably distorts ECG repolarization, in human research subjects. We are working closely with industry, through a Collaborative Research and Development Agreement, system for safe patient hemodynamic monitoring and recording during interventional MRI experiments and during transfer between X-ray and MRI. We are working closely with industry to transfer our developments into commercial tools that can be used widely in medical care throughout the world. Specifically we are working on ways to assure safety of conductive metallic catheter devices during real-time MRI.