Social determinants of cardiovascular disease risk over the life course

项目摘要 在过去的几十年里，心血管疾病（CVD）的发病率和心血管疾病危险因素的患病率 在中美洲地区稳步增加。该地区CVD的上升是同时发生的 随着社会不平等的扩大，阻碍了健康公平的进步，并构成了一个日益增长的，站不住脚的 有限的公共卫生和医疗保健系统的负担。培训和指导当地劳动力， 确定相关的研究问题，使用适当的研究方法，并在传播 向科学界、公众和政策制定者提供结果的信息， 在该地区预防CVD的干预措施。重要的是，包括人口的不同观点， 通过增加研究人员的多样性， 有代表的机构，增加了所有人口的卫生需求得到满足的可能性， 不平等现象减少。为此，来自德雷克塞尔大学和中央营养研究所的研究人员 美国和巴拿马（INCAP）已经建立了一个D43培训计划，重点是发展研究 培训人员的能力和地方能力建设，以便就 社会决定因素和基于地点的因素对整个生命周期心血管疾病风险的影响。拟议行政 补充将扩大现有的家长培训计划，包括两个合作机构，工作 在研究中代表性不足的人群。补充材料的培训活动利用 由家长培训计划创建的培训基础设施，将包括对博士后研究员的支持 和三名初级学者，以及注重方法的讲习班，以提高受训人员的分析能力。这些 这些活动将最终加强新的培训伙伴的机构研究能力， 通过提高参与强有力的南南合作的潜力， 合作。也就是说，通过帮助巩固加强南南合作的基础， INCAP和来自中美洲的两个伙伴机构， 将帮助INCAP加强对服务不足的土著和农村地区心血管疾病预防的研究 人口。因此，培训计划将有助于发展强大和可持续的研究 解决卫生不平等问题和满足中美洲所有人口卫生需求的能力 通过增加研究人员的多样性。

PROJECT SUMMARY Over the last several decades, cardiovascular disease (CVD) incidence and the prevalence of CVD risk factors have steadily increased in the Central American region. The rise of CVD in the region has occurred in tandem with widening social inequities that hamper progress toward health equity, and pose a growing, untenable burden for its limited public health and health care systems. Training and mentoring the local workforce in identifying relevant research questions, in the use of appropriate research methods, and in the dissemination of results to the scientific community, the public, and policy makers is critical to identify and develop interventions to prevent CVD in the region. Importantly, including diverse perspectives of the very populations with greatest health needs, through increasing the diversity of the research workforce and Central American institutions represented, increases the probability that the health needs of all populations are addressed and inequities are reduced. To this end, researchers from Drexel University and the Institute for Nutrition of Central America and Panama (INCAP) have established a D43 training program focused on developing the research capabilities of trainees and local capacity building in the conduct of policy-relevant research on the influence of social determinants and place-based factors on CVD risk across the lifespan. The proposed administrative supplement will extend the existing parent training program to include two partner institutions that work populations that have been underrepresented in research. Training activities for the supplement leverage the training infrastructure created by the parent training program and will include support for a postdoctoral fellow and three junior scholars, and methods-oriented workshops to increase analytical capacity of trainees. These activities will ultimately strengthen the institutional research capacity of new training partners, and, synergistically research capacity at INCAP by increasing its potential to engage in robust south-south collaborations. That is, by helping to solidify the foundation for increased south-south collaboration between INCAP and two partner institutions from Central America, the training goals of this administrative supplement will help INCAP strengthen its research on in CVD prevention among underserved indigenous and rural populations. Thus, the training program will contribute to developing a strong and sustainable research capacity that addresses health inequities and meets the health needs of all populations within Central America through increasing the diversity of the research workforce.