A High-Resolution Point-of-Care Neuro-MRI

描述（由申请人提供）：该项目旨在证明制造具有专门设计用于人体头部和C-脊柱成像的新型架构的逼真床旁MRI扫描仪的可行性。我们在MRI系统集成、超导磁体设计、超导导线技术和低温工程实用方法方面的独特能力使创新的MRI平台成为可能。扫描仪将基于1.5T（或更高）高均匀性磁体，其将是超导、无冷冻剂、持久模式和自屏蔽装置。扫描仪将使用专门设计的高级梯度和RF线圈，以及由市售组件构成的控制台（将在第二阶段中进行演示）。预期床旁MRI扫描仪的演示通过提供特定于应用的MRI磁体系统打开了神经成像新时代的大门，该系统具有低制造成本、低运营成本、易于安装以及患者和技术人员良好的人体工程学。该计划的目标与NIH/NIBIB与床旁技术发展相关的目标完全一致。公共卫生相关性：该计划旨在证明制造具有专门设计用于人体头部和C-脊柱成像的新型架构的逼真床旁MRI扫描仪的可行性。优化的MRI扫描仪的演示为特定应用的神经成像磁体系统的新时代打开了大门。它专门针对公共卫生的主要领域：中风和创伤。该计划的目标与NIH/NIBIB与床旁技术发展相关的目标完全一致。

DESCRIPTION (provided by applicant): This program aims to demonstrate the feasibility of manufacturing a realistic Point-Of-Care MRI scanner with a novel architecture specifically designed for imaging the human head and C- spine. The innovative MRI platform is made possible by our unique capabilities in MRI system integration, superconducting magnet design, superconducting wire technology, and pragmatic approaches to cryogenic engineering. The scanner would be based on a 1.5 T (or higher) high homogeneity magnet that would be a superconducting, cryogen-free, persistent mode, and self- shielded device. The scanner would use specifically designed advanced gradient and RF coils, and a console constructed from commercially available components, (those to be demonstrated in Phase II). Demonstrations of the intended Point-Of-Care MRI scanner opens the door to a new era in neurological imaging by offering an application-specific MRI magnet system with: low manufacturing cost, low operational cost, easy installation, and good ergonomics for the patient and technologists. The goals of the program are well in line with the NIH/NIBIB goals related to the development of Point-of-Care Technologies. PUBLIC HEALTH RELEVANCE: This program aims to demonstrate the feasibility of manufacturing a realistic Point-Of-Care MRI scanner with a novel architecture specifically designed for imaging the human head and C- spine. Demonstrations of the optimized MRI scanner opens the door to a new era in application-specific neurological imaging magnet systems. It is specifically addressed at the major areas of public health: stroke and trauma. The goals of the program are well in line with the NIH/NIBIB goals related to the development of Point-of-Care Technologies.