Vision Research Training Program

描述（由申请人提供）：我们在斯坦福大学眼科学系和视力和防盲中心正在申请国家眼科研究所的T32培训补助金，以资助一个旨在整合基础视力研究和临床眼科培训的博士后项目。我们的目标包括：1）强化临床眼科暴露，特别是针对未经临床培训的研究人员，以促进基础视觉研究的未来临床应用; 2）促进医学博士的过渡。还有医学博士博士学位-临床实习生 实践严格的视觉研究和促进他们的成功申请职业发展（K）奖，一个重要的资助机制，为医生科学家;和3）教育和培训的基础和临床研究人员从不同背景的分子，细胞，突触，和系统水平的视觉研究，为他们准备在临床和基础部门的学术生涯。在你的帮助下，我们计划训练4个医学博士，哲学博士、或者医学博士博士研究员每年。基础视觉研究和眼科学强化课程（眼科302 A），每周一次的多学科斯坦福大学视觉和预防失明中心讲座和研讨会，以及其他视觉课程和流行病学和统计学培训将是根据每个学员的背景和研究兴趣量身定制的教育计划，沿着每年有机会展示他们的工作，教学，撰写资助申请，参加科学会议。 每位学员将被分配一名基础科学和一名临床导师，导师从斯坦福大学视觉研究人员中选出，这些研究人员总共拥有国家眼科研究所的16项R 0 l赠款，并发表了100多篇同行评审文章 出版物在过去两年。这些导师帮助每个学员发表基础和临床论文，作为严格的科学和临床调查的例子，并帮助制定一个全面的计划，以交织在基本领域的知识，如眼睛和视觉电路的发育模式，突触可塑性和视觉通路的处理，视觉物体识别和阅读，和视觉运动整合，详细了解低视力和失明的常见原因的诊断和治疗以及用于解决这些问题的工具。一个外部咨询委员会就该方案的运作提供独立的观点。 公共卫生相关性：由于我们的计划旨在为每位学员提供对视力研究及其应用的全面了解，以防止视力丧失，我们的学员准备做出重大的研究贡献，以解决失明和低视力的不同原因，它影响着全球1.6亿人，仅考虑主要的成年人，视觉障碍

DESCRIPTION (provided by applicant): We at the Stanford Department of Ophthalmology and Center for Vision and Prevention of Blindness are applying for a T32 Training Grant from the National Eye Institute to fund a the post-doctoral program designed to Integrate basic vision research and clinical ophthalmologic training. Our goals include: 1) intensive clinical ophthalmologic exposure, especially targeting non-clinically trained investigators, to facilitate future bench-to-bedside applications of basic vision research; 2) facilitation of the transition of M.D. and M.D.-Ph.D.-trainees from clinical practice to rigorous vision research and fostering their successful application to the Career development (K) Award, an important funding mechanism for physician-scientists; and 3) the education and training of basic and clinical investigators from diverse backgrounds in molecular, cellular, synaptic, and systems level vision research to prepare them for academic careers in clinical and basic departments. With your help, we plan to train 4 M.D., Ph.D., or M.D.-Ph.D. fellows per year. An intensive course on basic vision research and ophthalmology (Ophthalmology 302A), weekly multi-disciplinary Stanford Center for Vision and Prevention of Blindness lectures and seminars, and other vision courses and training in epidemiology and statistics will be among the educational program tailored to each trainee's background and research interest, along with annual opportunities to present their work, teach, write grant applications, and attend scientific meetings. Each trainee will be assigned a basic science and a clinical mentor, chosen from Stanford vision investigators which collectively hold 16 R0l grants from the National Eye Institute and have published over 100 peer-reviewed publications in the last 2 years. These mentors help each trainee publish basic and clinical papers, serve as examples of rigorous scientific and clinical Investigations, and help develop a well-rounded program to interweave knowledge in basic areas such as developmental patterning of the eye and visual circuitry, synaptic plasticity and processing of the visual pathway, visual object recognition and reading, and visual-motor integration with a detailed understanding of the diagnosis and treatment of common causes of low vision and blindness and tools used to address them. An External Advisory Committee offers independent perspectives on the Program's operation. PUBLIC HEALTH RELEVANCE: Because our program is designed to provide each trainee with a comprehensive understanding of vision research and its applications to prevent vision loss, our trainees are poised to make significant research contributions to tackle the different causes of blindness and low vision, which affects 160 million people worldwide and costs the United States annually 35.4 billion dollars in financial burden when considering just the major adult visual disorders.