UNC-Duke Collaborative Clinical Pharmacology Postdoctoral Training Program

 描述（由申请人提供）：位于查佩尔山的北卡罗来纳州大学（北卡罗来纳州）与杜克大学和Hamner-Schmidt药物安全科学研究所（IDSS）合作，在临床药理学方面拥有成功的T32培训计划，该计划建立在我们卓越的研究环境基础上，在药物发现，药物开发，儿科临床药理学，药物基因组学和药物安全性方面拥有世界一流的计划。我们在临床药理学培训临床医生-科学家方面有着出色的记录， 和多元化的申请人池与更多的合格申请人比资助的职位。我们在此更新申请中详细介绍的培训计划提供了强大的领导力，来自多个学科的国际公认的导师，他们积极参与临床药理学，广泛的尖端技术和资源，以及具有强大机构支持的独特协作环境。该计划的国家申请人库来自医学专业培训计划中的医学博士，他们寻求临床药理学的职业道路，以及高级临床/转化研究培训中的药学博士。学员在个性化指导团队的指导下完成临床药理学课程，并参与特定项目的活动，以获得当代临床药理学研究各个方面的专业知识，从药代动力学，药物计量学和药物基因组学到临床试验设计和伦理学。教师导师的选择是基于他们的研究生产力在至少四个重点领域之一，形成这个培训计划的核心：药物处置和行动;定量药理学和临床试验设计;药物基因组学;药物诱导的器官毒性。该培训计划的一个独特之处是我们专注于临床药理学的未充分研究领域，特别是儿科和药物安全性。我们的实习生对临床药理学的浓厚兴趣，在所有三个机构中对临床药理学研究资源的无与伦比的投资，三角研究园智力丰富的生物医学科学环境，以及我们长期以来优秀的研究和培训基础设施联合收割机相结合，创造了临床药理学培训无与伦比的机会。

 DESCRIPTION (provided by applicant): The University of North Carolina at Chapel Hill (UNC), in collaboration with Duke University and the Hamner-UNC Institute for Drug Safety Sciences (IDSS), has a successful T32 training program in clinical pharmacology that builds on our exceptional research environment with world-class programs in drug discovery, drug development, pediatric clinical pharmacology, pharmacogenomics, and drug safety. We have an outstanding track record of training clinician-scientists in clinical pharmacology and an excellent and diverse applicant pool with many more qualified applicants than funded positions. Our training program detailed in this renewal application offers strong leadership, internationally-recognized mentors from multiple disciplines who are actively involved in clinical pharmacology, a wide-array of cutting edge technologies and resources, and a uniquely collaborative environment with strong institutional support. The national applicant pool for this program is derived both from MDs in medical specialty training programs seeking a career path in clinical pharmacology and PharmDs in advanced clinical/translational research training. Trainees, guided by individualized mentoring teams, complete clinical pharmacology coursework and engage in program-specific activities to gain expertise in all aspects of contemporary clinical pharmacology research, from pharmacokinetics, pharmacometrics and pharmacogenomics to clinical trial design and ethics. Faculty mentors are chosen based on their research productivity in at least one of four focus areas that form the core of this training program: Drug Disposition and Action; Quantitative Pharmacology and Clinical Trial Design; Pharmacogenomics; Drug-induced Organ Toxicity. A unique feature of this training program is our focus on understudied areas in clinical pharmacology, specifically pediatrics and drug safety. The keen interest in clinical pharmacology within our trainee pool, the unparalleled investment in clinical pharmacology research resources at all three institutions, the intellectually-rich biomedical science environment of Research Triangle Park, and our longstanding excellent research and training infrastructure combine to create a moment of unsurpassed opportunity for training in clinical pharmacology.