Targeting nucleic acid synthesis and cell division in Gram-negative bacterial pathogens

一些细菌，如不动杆菌，会在医院引起难以治疗的感染，因为它们已经对大多数抗生素产生了抗药性。该项目将结合五个研究小组的互补专业知识，以开发知识以及如何阻止这些令人担忧的病原体物种的三个基本过程：DNA复制、RNA合成和细胞分裂。这有望导致新的抗菌疗法的开发。

Some bacteria like Acinetobacter species cause infections in hospitals that are difficult to treat because they have acquired resistance to most antibiotics. This project will combine the complementary expertise of five research groups to develop knowledge of, and how to block, three essential processes in these worrying pathogenic species: copying of DNA, RNA synthesis, and cell division. This promises to lead to development of new antibacterial therapies.