Development of encapsulation materials and design for implantable 3D bioprinted pancreatic cells

新兴的细胞疗法有可能极大地改善个人的健康，并通过改善损伤或治愈疾病的治疗来降低医疗成本。例如，已经确定细胞移植疗法可以逆转并可能治愈1型糖尿病。然而，开发可靠和经济的哺乳动物细胞制造和递送这些疗法的方法对于确保许多有前途的新兴医疗保健技术广泛提供给需要它们的患者至关重要。因此，这些新兴疗法的巨大前景伴随着巨大的挑战，其中许多是本项目所涉及的细胞培养过程和设备工程领域的挑战。最终，增加获得安全和负担得起的细胞培养产品的机会将改善成千上万加拿大人的生活质量。 UBC和加拿大多学科小组是这一研究领域的领导者。出口这些技术和知识将使世界各地的人民受益，并为加拿大人带来巨大的商业利益。

Emerging cellular therapies have the potential to both greatly improve the health of individuals and to reduce healthcare costs with improved treatments for injuries or curing diseases. For example, it has been established that a cellular transplant therapy can reverse and potentially cure type 1 diabetes. However, the development of reliable and economical means of mammalian cell manufacturing and delivery of these therapies is essential to ensure that many promising emerging health care technologies become widely available to the patients who need them. Thus, the great promise of these emerging treatments comes with great challenges, many of those in the field of cell culture process and device engineering that this project addresses. Ultimately, increased access to safe and affordable cell culture products will improve the quality of many thousands of Canadian lives. UBC and Canadian multidisciplinary groups are among the leaders in this area of research. Exporting these technologies and knowledge should benefit populations around the world as well as translate into substantial commercial benefits for Canadians.