Organic Transformations with eta2-Arene Complexes
eta2-芳烃配合物的有机转化
基本信息
- 批准号:9212008
- 负责人:
- 金额:$ 24.46万
- 依托单位:
- 依托单位国家:美国
- 项目类别:Continuing Grant
- 财政年份:1992
- 资助国家:美国
- 起止时间:1992-07-15 至 1996-06-30
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
Coordinated arenes can serve as valuable synthons to a variety of mono-and polycyclic natural products when used in conjunction with an appropriate dihapto-coordination agent. In order to test and develop this hypothesis, the research program will address three primary questions: i) what organic transformations can be accomplished through such a technology that are difficult to achieve by conventional methods, ii) to what extent can the stereochemistry of such transformations be controlled by the transition metal, and iii) how can the nature of the complexing agent be modified to achieve a) greater activation of the aromatic substrate b) asymmetric induction, and c) a catalytic cycle for various target reactions? %%% With this award, the Organic Synthesis Program will support the research of Dr. W. Dean Harman at the University of Virginia. The research will develop the reactions of coordinated arene transition metal complexes to form substituted cyclic products which has the effect of shortening certain synthetic sequences. This new synthetic methodology should benefit research in biochemistry and medicine as well as in the chemical industry.
当配位芳烃与适当的二氢配位剂一起使用时,可以作为各种单环和多环天然产物的有价值的合成子。为了测试和发展这一假说,研究计划将解决三个主要问题:i)通过这种技术可以实现哪些用传统方法难以实现的有机转变,ii)这种转变的立体化学可以在多大程度上由过渡金属控制,以及iii)如何改变络合剂的性质以实现a)芳香族底物的更大活性b)不对称诱导,以及c)用于各种目标反应的催化循环?有机合成计划将支持弗吉尼亚大学W·迪恩·哈曼博士的研究。这项研究将发展配位芳烃过渡金属络合物的反应,形成取代的环状产物,具有缩短某些合成序列的效果。这种新的合成方法应该有利于生物化学和医学以及化学工业的研究。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
Walter Harman其他文献
Walter Harman的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('Walter Harman', 18)}}的其他基金
MRI: Acquisition of a rapid-throughput NMR spectrometer at the University of Virginia
MRI:在弗吉尼亚大学购买快速通量核磁共振波谱仪
- 批准号:
2215062 - 财政年份:2022
- 资助金额:
$ 24.46万 - 项目类别:
Standard Grant
High-Precision Synthesis and Analysis of Deuterated Cycloalkene Isotopomers
氘代环烯同位素异构体的高精度合成与分析
- 批准号:
2100345 - 财政年份:2021
- 资助金额:
$ 24.46万 - 项目类别:
Standard Grant
Molybdenum-Promoted Dearomatization Reactions
钼促进的脱芳构化反应
- 批准号:
1800051 - 财政年份:2018
- 资助金额:
$ 24.46万 - 项目类别:
Standard Grant
Organic Transformations with Dihapto-Coordinated Arene Complexes
双键配位芳烃配合物的有机转化
- 批准号:
1152803 - 财政年份:2012
- 资助金额:
$ 24.46万 - 项目类别:
Continuing Grant
Organic Transformations of eta-2-Arene Complexes
eta-2-芳烃配合物的有机转化
- 批准号:
0748986 - 财政年份:2008
- 资助金额:
$ 24.46万 - 项目类别:
Continuing Grant
Organic Transformations with Dihapto-Coordinated Arene Complexes
双键配位芳烃配合物的有机转化
- 批准号:
0452016 - 财政年份:2005
- 资助金额:
$ 24.46万 - 项目类别:
Continuing Grant
Organic Transformations with h2-Arene Complexes of Rhenium
铼的 h2-芳烃配合物的有机转化
- 批准号:
0111558 - 财政年份:2001
- 资助金额:
$ 24.46万 - 项目类别:
Continuing Grant
Organic Transformations of eta-2- Arene Complexes
eta-2-芳烃配合物的有机转化
- 批准号:
9807375 - 财政年份:1998
- 资助金额:
$ 24.46万 - 项目类别:
Standard Grant
Organic Transformations of n2-Arene Complexes
n2-芳烃配合物的有机转化
- 批准号:
9509883 - 财政年份:1995
- 资助金额:
$ 24.46万 - 项目类别:
Continuing Grant
NSF Young Investigator: Pi-Base Promoted Activation of Aromatic Molecules
NSF 青年研究员:Pi 基促进芳香分子的活化
- 批准号:
9357125 - 财政年份:1993
- 资助金额:
$ 24.46万 - 项目类别:
Continuing Grant
相似海外基金
Contorted and Strained Molecular Nanographenes: Multi-Electron Storage and Reduction-Induced Transformations
扭曲和应变的分子纳米石墨烯:多电子存储和还原诱导的转变
- 批准号:
2404031 - 财政年份:2024
- 资助金额:
$ 24.46万 - 项目类别:
Continuing Grant
Resource Struggles and International Law: Navigating Global Transformations
资源斗争和国际法:引领全球变革
- 批准号:
DE240100131 - 财政年份:2024
- 资助金额:
$ 24.46万 - 项目类别:
Discovery Early Career Researcher Award
Alkane transformations through binding to metals
通过与金属结合进行烷烃转化
- 批准号:
DP240103289 - 财政年份:2024
- 资助金额:
$ 24.46万 - 项目类别:
Discovery Projects
Collaborative Research: CAS: Exploration and Development of High Performance Thiazolothiazole Photocatalysts for Innovating Light-Driven Organic Transformations
合作研究:CAS:探索和开发高性能噻唑并噻唑光催化剂以创新光驱动有机转化
- 批准号:
2400166 - 财政年份:2024
- 资助金额:
$ 24.46万 - 项目类别:
Continuing Grant
The role of indoor dust in modulating indoor air chemistry: assessing air-dust heterogeneous transformations and human exposures
室内灰尘在调节室内空气化学方面的作用:评估空气-灰尘异质转化和人体暴露
- 批准号:
2341756 - 财政年份:2024
- 资助金额:
$ 24.46万 - 项目类别:
Standard Grant
DMS/NIGMS 1: Multilevel stochastic orthogonal subspace transformations for robust machine learning with applications to biomedical data and Alzheimer's disease subtyping
DMS/NIGMS 1:多级随机正交子空间变换,用于稳健的机器学习,应用于生物医学数据和阿尔茨海默病亚型分析
- 批准号:
2347698 - 财政年份:2024
- 资助金额:
$ 24.46万 - 项目类别:
Continuing Grant
Collaborative Research: CAS: Exploration and Development of High Performance Thiazolothiazole Photocatalysts for Innovating Light-Driven Organic Transformations
合作研究:CAS:探索和开发高性能噻唑并噻唑光催化剂以创新光驱动有机转化
- 批准号:
2400165 - 财政年份:2024
- 资助金额:
$ 24.46万 - 项目类别:
Continuing Grant
Musical Transformations: Collaborative music making with people of marginalised genders
音乐变革:与边缘化性别人士合作创作音乐
- 批准号:
2891450 - 财政年份:2023
- 资助金额:
$ 24.46万 - 项目类别:
Studentship
LEAPS-MPS: Cooperative Transformations of N-Heterocycles with Heterometallic Complexes
LEAPS-MPS:N-杂环与异金属配合物的协同转化
- 批准号:
2316582 - 财政年份:2023
- 资助金额:
$ 24.46万 - 项目类别:
Standard Grant