Organic Transformations of n2-Arene Complexes

n2-芳烃配合物的有机转化

• 批准号: 9509883
• 负责人: Walter Harman
• 金额: $ 29.4万
• 依托单位: University of Virginia Main Campus
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1995
• 资助国家: 美国
• 起止时间: 1995-07-01 至 1998-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9509883&HistoricalAwards=false
• 关键词: Organic; Transformations; n2; Arene; Complexes

The focus of this research is the dearomatization of aromatics by use of n2-arene complexes of osmium(II). The osmium(II) activates the aromatic system to electrophilic addition and provides a powerful new synthetic approach to dearomatization and the use of aromatic systems for the preparation of polycyclic organic compounds.With this renewal award, the Synthetic Organic Program is supporting the research of Dr. W. Dean Harman of the Department of Chemistry at the University of Virginia. Professor Harman will focus his work on determining the role of transition metals, specifically osmium(II) complexes of arenes, as dearomatizing agents for organic synthesis.

本研究的重点是利用锇（II）的n2-芳烃配合物对芳烃进行脱芳化。锇（II）激活芳系进行亲电加成，为芳系脱芳和制备多环有机化合物提供了强有力的新合成途径。有了这个更新奖，合成有机项目支持弗吉尼亚大学化学系的W. Dean Harman博士的研究。哈曼教授的工作重点是确定过渡金属的作用，特别是芳烃的锇（II）配合物，作为有机合成的脱芳剂。