Global repeat discovery of rye A and B chromosomes using a high-throughput 454 sequence survey
Global repeat discovery of rye A and B chromosomes using a high-throughput 454 sequence survey
批准号:
161180062
负责人:
Privatdozent Dr. Andreas Houben
金额:
$0.0万
依托单位国家:
德国
项目类别:
Research Grants
财政年份:
2010
资助国家:
德国
项目状态:
已结题
起止时间:
2009-12-31 至 2013-12-31
中文摘要
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英文摘要
We aim to reconstruct the first representative dataset of rye highly-repetitive sequences in silico on a whole-genome scale. We will use a high-throughput 454 sequence survey for comparative analysis of the repeat composition with other grass species, for an improved analysis of large genomes. The sequence analysis of flow-sorted rye B chromosomes (Bs) will allow insights in the evolution of Bs. The chromosomal distribution of repeat families will be determined experimentally to establish chromosome specific makers. This analysis will provide new evidence for the generation of rapid genome changes in higher eukaryotes, with particular relevance to selfish chromosomes.
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