Reactions at Ligands in Strongly Oxidizing Metal Complexes

强氧化性金属配合物中配体的反应

• 批准号: 0513023
• 负责人: James Mayer
• 金额: $ 44.6万
• 依托单位: University of Washington
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-07-01 至 2009-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0513023&HistoricalAwards=false
• 关键词: Reactions; Ligands; Strongly; Oxidizing; Metal

Professor James M. Mayer of the University of Washington is supported by the Inorganic, Bioinorganic and Organometallic Chemistry Program to explore oxidation reactions utilizing high oxidation state metal complexes as reagents. Details of the oxidation of saturated hydrocarbons with osmium tetraoxide as the oxidant are being probed to provide an understanding of oxidation reactions of organic substrates. Monomeric ruthenium and iridium complexes with four d electrons will be used as reagents with the goal of promoting ligand-based redox chemistry. Oxidation reactions are essential to industrial chemistry, biochemistry and organic synthesis. The environmental impact of oxidation reactions is also an area of global importance. This project will generate mechanistic information that will guide the design of new oxidation reagents and catalysts. This project will develop metal complexes for use as more efficient and more selective oxidation reagents.

华盛顿大学的James M. Mayer教授在无机、生物无机和有机金属化学项目的支持下，利用高氧化态金属配合物作为试剂，探索氧化反应。以四氧化锇为氧化剂的饱和碳氢化合物氧化的细节正在被探索，以提供对有机底物氧化反应的理解。具有四个电子的钌和铱单体配合物将被用作试剂，目的是促进基于配体的氧化还原化学。氧化反应在工业化学、生物化学和有机合成中是必不可少的。氧化反应对环境的影响也是一个具有全球重要性的领域。该项目将产生机械信息，将指导新的氧化试剂和催化剂的设计。该项目将开发金属配合物，作为更有效和更有选择性的氧化试剂。