Biophotonics: Towards Nondestructive Optical Analysis of Nanostructures Using Photonic Nanojets
生物光子学:利用光子纳米喷射对纳米结构进行无损光学分析
基本信息
- 批准号:0522639
- 负责人:
- 金额:$ 19.94万
- 依托单位:
- 依托单位国家:美国
- 项目类别:Standard Grant
- 财政年份:2005
- 资助国家:美国
- 起止时间:2005-07-01 至 2008-06-30
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
Backman0522639This proposal seeks to experimentally demonstrate and characterize photonic nanojets. Nanojets are created through the local field enhancement of micro-spheres or micro-cylinders and greatly enhance the backscattering of small nanoparticles that are located within their extent. Rigorous FDTD calculations by the investigators have shown that the intensity and angular distribution of backscattered nanoparticles in the nanojets are highly dependent upon the particle size. A unique feature of the nanojets lies in the fact that they are neither diffracting nor evanescent. The investigators propose to use the nanojets as a new sorting method for nanoshells in order to obtain a uniform size distribution to obtain better spectral selectivity in imaging applications. Applications of the nanojets to sorting intracellular macromolecules are also proposed.
Backman0522639该提案寻求实验证明和表征光子纳米喷射。纳米射流是通过微球或微柱的局部场增强产生的,并且极大地增强了位于其范围内的小纳米颗粒的后向散射。研究人员进行的严格的FDTD计算表明,纳米射流中背散射纳米颗粒的强度和角分布高度依赖于颗粒尺寸。纳米喷射的独特特征在于它们既不衍射也不消逝。研究人员建议使用纳米喷射作为纳米壳的新分选方法,以获得均匀的尺寸分布,从而在成像应用中获得更好的光谱选择性。纳米喷射分选细胞内大分子的应用也提出了。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Vadim Backman其他文献
Sa1712 Differential Effects of Tumor-Promoting and Tumor-Inhibiting Dietary Fats on Angiogenesis in Normal and Tumor-Bearing Colon
- DOI:
10.1016/s0016-5085(13)61025-2 - 发表时间:
2013-05-01 - 期刊:
- 影响因子:
- 作者:
Vani J. Konda;Mariano Gonzalez-Haba Ruiz;Sarah Ruderman;Vesta Valuckaite;Urszula Dougherty;Reba Mustafi;Anirudh Kulkarni;Tiffany Chua;Irving Waxman;Vadim Backman;John Hart;Marc Bissonnette - 通讯作者:
Marc Bissonnette
Influence of Micropillar Induced Deformation on Chromatin Architecture in Regulating Stem Cell Differentiation
- DOI:
10.1016/j.bpj.2019.11.2999 - 发表时间:
2020-02-07 - 期刊:
- 影响因子:
- 作者:
Vasundhara Agrawal;Xinlong Wang;Guillermo Ameer;Vadim Backman - 通讯作者:
Vadim Backman
Differential unfolded protein response regulation in KRAS silencing sensitive and innately resistant colorectal cancer cells
KRAS 沉默敏感和先天耐药结直肠癌细胞中差异展开的蛋白反应调节
- DOI:
10.1038/s41598-025-94549-2 - 发表时间:
2025-04-24 - 期刊:
- 影响因子:3.900
- 作者:
Flávia Martins;Ana L. Machado;Joana Carvalho;Catarina R. Almeida;Hans C. Beck;Ana S. Carvalho;Vadim Backman;Rune Matthiesen;Sérgia Velho - 通讯作者:
Sérgia Velho
Bridging Chromatin Nanoimaging and Molecular Modeling: Chromatin Packing as a Regulator of Transcriptional Heterogeneity in Carcinogenesis
- DOI:
10.1016/j.bpj.2019.11.3007 - 发表时间:
2020-02-07 - 期刊:
- 影响因子:
- 作者:
Vadim Backman - 通讯作者:
Vadim Backman
Large-Scale Heteropolymer Model of Chromatin Dynamics and Mechanics
- DOI:
10.1016/j.bpj.2019.11.3011 - 发表时间:
2020-02-07 - 期刊:
- 影响因子:
- 作者:
Anne Shim;Kai Huang;Vadim Backman;Igal Szleifer - 通讯作者:
Igal Szleifer
Vadim Backman的其他文献
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{{ truncateString('Vadim Backman', 18)}}的其他基金
EFRI CEE: Macrogenomic engineering via modulation of chromatin nanoenvironment
EFRI CEE:通过调节染色质纳米环境进行宏观基因组工程
- 批准号:
1830961 - 财政年份:2018
- 资助金额:
$ 19.94万 - 项目类别:
Standard Grant
EFRI-BioFlex: Miniature, low-cost fiber-optics technology for measurement of tissue structure at sub-diffractional length scales: a platform for cancer screening
EFRI-BioFlex:用于在亚衍射长度尺度上测量组织结构的微型、低成本光纤技术:癌症筛查平台
- 批准号:
1240416 - 财政年份:2012
- 资助金额:
$ 19.94万 - 项目类别:
Standard Grant
EAGER: New Biophotonics and Computational Molecular Dynamics for Understanding Epigenetic Regulation of Gene Transcription
EAGER:新生物光子学和计算分子动力学用于理解基因转录的表观遗传调控
- 批准号:
1249311 - 财政年份:2012
- 资助金额:
$ 19.94万 - 项目类别:
Standard Grant
MRI-R2: Development of biophotonics instrumentation for sensing subcellular structure at nanoscale
MRI-R2:开发用于传感纳米级亚细胞结构的生物光子学仪器
- 批准号:
0960148 - 财政年份:2010
- 资助金额:
$ 19.94万 - 项目类别:
Standard Grant
EAGER: BISH: Biophotonics Technique for Detection of Lung Cancer
EAGER:BISH:用于检测肺癌的生物光子学技术
- 批准号:
0939778 - 财政年份:2009
- 资助金额:
$ 19.94万 - 项目类别:
Standard Grant
EFRI-BSBA: Photonic Technique for Sensing and Understanding Subcellular Structures at Nanoscale
EFRI-BSBA:用于传感和理解纳米级亚细胞结构的光子技术
- 批准号:
0937987 - 财政年份:2009
- 资助金额:
$ 19.94万 - 项目类别:
Standard Grant
SGER: Biophotonics for Diagnosis of Pancreatic Cancer
SGER:用于诊断胰腺癌的生物光子学
- 批准号:
0733868 - 财政年份:2007
- 资助金额:
$ 19.94万 - 项目类别:
Standard Grant
SGER: Biophotonics Techniques for Accurate Diagnosis of Pancreatic Cancer
SGER:准确诊断胰腺癌的生物光子学技术
- 批准号:
0620303 - 财政年份:2006
- 资助金额:
$ 19.94万 - 项目类别:
Standard Grant
SGER: Noninvasive Detection of Pancreatic Cancer Using Biophotonics Techniques
SGER:利用生物光子技术无创检测胰腺癌
- 批准号:
0547480 - 财政年份:2005
- 资助金额:
$ 19.94万 - 项目类别:
Standard Grant
SGER: Development of Minimally Invasive Optical Technique for Early Detection of Pancreatic Cancer
SGER:开发用于早期检测胰腺癌的微创光学技术
- 批准号:
0417689 - 财政年份:2004
- 资助金额:
$ 19.94万 - 项目类别:
Standard Grant
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