SGER: Biophotonics for Diagnosis of Pancreatic Cancer

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CBET-0733868 Backman Pancreatic cancer (PC) has the worst prognosis of any major cancer, with a five-year survival rate below 5%. The reasons for the lethality of PC relates to its tendency to bediagnosed at a late stage given that potentially curable stages of disease are oftenclinically silent. Survival rate dramatically depends on the stage at which PC isdiagnosed. However, pancreatic cancer is insidious in that the development of symptomsgenerally portend unresectable and hence uncurable disease. One of the major hurdlespreventing screening for PC is that essentially any interrogation of the pancreas may leadto serious complications (~20% complication rate). Thus, finding a pre-screening method inwhich patients are risk-stratified would be critical for designing screening strategies.This project focuses on development of a biophotonics approach (a partial wave spectroscopic microscopic technique), to address this problem.