MRI: Development of an photonic force microscopic system for visualization and manipulation of biological structures and Systems

MRI：开发光子力显微系统，用于生物结构和系统的可视化和操纵

• 批准号: 0619472
• 负责人: Chia-Hsiang Menq
• 金额: $ 46.45万
• 依托单位: Ohio State University Research Foundation -DO NOT USE
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-10-01 至 2010-03-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0619472&HistoricalAwards=false
• 关键词: MRI; Development; photonic; force; microscopic

0619472MenqThe research group proposes to develop a photonic force microscopic (PFM) system for automated 3D visualization and controlled manipulation of biological structures and systems under physiological condition and at multiple scales ranging from mm to nm. Five (5) subsystems will be integrated. While dealing living entity, the PFM system uses feedback control based on photonic trapping that can achieve more stable and high precision performance for imaging. If the system is successfully integrated with a confocal microscope for automated 3D visual guidance, as proposed in the grant, a new frontier of basic research in nanoscale structure on diversity living systems can be anticipated.

0619472Menq研究小组提出开发一种光子力显微镜（PFM）系统，用于在生理条件下和从mm到nm的多个尺度上对生物结构和系统进行自动3D可视化和控制操作。将集成五（5）个子系统。在处理生物体时，PFM系统采用基于光子捕获的反馈控制，可以获得更稳定、更高精度的成像性能。如果该系统成功地与共聚焦显微镜集成，用于自动3D视觉引导，正如拨款中所提出的那样，可以预期在多样性生命系统的纳米结构基础研究中的新前沿。