MRI: Acquisition of a cryoprobe- and autosampler-equipped AVANCE III 500 MHz solution NMR

蒙大拿州立大学获得了购买布鲁克AVANCE III 500 MHz核磁共振光谱仪的合同，该光谱仪配备了灵敏度增强的Prodigy TM宽带冷冻探针。新文书将加强各级的研究和教育。它将通过使学生在新的，强大的小分子核磁共振分析技术方面的培训，对研究生和本科生的教育都有很大的好处。密歇根州立大学为学生提供最先进仪器的直接实践培训，从夏季本科生研究项目到大二有机实验室课程，再到研究生水平的教学项目，都有授课。新的AVANCE III 500 NMR具有增强的功能，还将使他们能够通过远程仪器访问增强少数民族美国土著学生的参与，这将为在蒙大拿州偏远部落学院和全州其他小型学院就读科学课程的学生提供NMR光谱。配备低温探针的AVANCE III 500 NMR将允许研究人员使用NMR进行化学结构解析和小分子代谢物的全局分析（例如代谢组学）研究，将通过允许更高通量的数据收集来增强使用，并将促进固有低选择性应用的研究。此外，新仪器将成为蒙大拿州立大学的主要核磁共振光谱仪，并将极大地扩展蒙大拿州立大学的核磁共振研究能力，以获取小分子的多维（1D, 2D, 3D/nD）异核（1H, 13C, 15N, 31P）核磁共振光谱。新仪器将取代密歇根州立大学老化的500核磁共振光谱仪，将提高研究效率和学生教育。新仪器对于维持大学的研究生产力、教育质量和外展使命以及成功招聘新教师是绝对必要的。

An award is made to Montana State University to purchase a Bruker AVANCE III 500 MHz NMR spectrometer equipped with a sensitivity-enhanced Prodigy TM broadband cryoprobe. The new instrument will enhance research and education at all levels. It will strongly benefit student education at both the graduate and the undergraduate level by enabling student training in new, powerful small molecule NMR analytical techniques. MSU provides direct, hands-on training to students in state-of-the-art instrumentation, which is taught in venues ranging from summer undergraduate research programs to sophomore organic laboratory courses to graduate level instructional programs. The new AVANCE III 500 NMR with its enhanced capabilities will also enable them to enhance participation of minority Native American students through remote instrument access that will provide NMR spectra to students enrolled in sciences classes at remote Montana Tribal Colleges and at other small colleges across the state.The cryoprobe-equipped AVANCE III 500 NMR will allow researchers to use NMR for chemical structure elucidation and the global analysis of small molecule metabolites (e.g. metabolomics) research, will enhance usage by permitting higher throughput data collection, and will facilitate studies in applications with inherently low selectivity. In addition, the new instrument will be the workhorse NMR spectrometer for the university and will greatly expand Montana State University's NMR research capabilities for acquisition of multidimensional (1D, 2D, 3D/nD) heteronuclear (1H, 13C, 15N, 31P) NMR spectra of small molecules. The new instrumentation, which will replace MSU's aged 500 NMR spectrometer, will boost research productivity and student education. The new instrument is absolutely essential to maintain the university's research productivity, educational quality, and outreach mission, and for successful recruitment of new faculty.