MRI: Acquisition of a cryoprobe- and autosampler-equipped AVANCE III 500 MHz solution NMR

MRI：采集配备冷冻探头和自动进样器的 AVANCE III 500 MHz 解决方案 NMR

• 批准号: 1532078
• 负责人: Valerie Copie
• 金额: $ 50.41万
• 依托单位: Montana State University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-08-15 至 2018-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1532078&HistoricalAwards=false
• 关键词: MRI; Acquisition; cryoprobe; autosampler; equipped

An award is made to Montana State University to purchase a Bruker AVANCE III 500 MHz NMR spectrometer equipped with a sensitivity-enhanced Prodigy TM broadband cryoprobe. The new instrument will enhance research and education at all levels. It will strongly benefit student education at both the graduate and the undergraduate level by enabling student training in new, powerful small molecule NMR analytical techniques. MSU provides direct, hands-on training to students in state-of-the-art instrumentation, which is taught in venues ranging from summer undergraduate research programs to sophomore organic laboratory courses to graduate level instructional programs. The new AVANCE III 500 NMR with its enhanced capabilities will also enable them to enhance participation of minority Native American students through remote instrument access that will provide NMR spectra to students enrolled in sciences classes at remote Montana Tribal Colleges and at other small colleges across the state.The cryoprobe-equipped AVANCE III 500 NMR will allow researchers to use NMR for chemical structure elucidation and the global analysis of small molecule metabolites (e.g. metabolomics) research, will enhance usage by permitting higher throughput data collection, and will facilitate studies in applications with inherently low selectivity. In addition, the new instrument will be the workhorse NMR spectrometer for the university and will greatly expand Montana State University's NMR research capabilities for acquisition of multidimensional (1D, 2D, 3D/nD) heteronuclear (1H, 13C, 15N, 31P) NMR spectra of small molecules. The new instrumentation, which will replace MSU's aged 500 NMR spectrometer, will boost research productivity and student education. The new instrument is absolutely essential to maintain the university's research productivity, educational quality, and outreach mission, and for successful recruitment of new faculty.

授予蒙大拿州立大学一项合同，购买一台配备灵敏度增强型Prodigy TM宽带冷冻探针的Bruker AVANCE III 500 MHz NMR光谱仪。新的文书将加强各级的研究和教育。它将极大地有利于学生教育在研究生和本科水平，使学生培训新的，强大的小分子核磁共振分析技术。MSU为学生提供直接的实践培训，提供最先进的仪器，这些仪器在从夏季本科研究课程到大二有机实验室课程到研究生水平教学课程的场所教授。新的AVANCE III 500 NMR具有更强的功能，还将使他们能够通过远程仪器访问来提高少数民族美国土著学生的参与度，这将为偏远的蒙大拿部落学院和全州其他小型学院的科学课程学生提供NMR光谱。装备AVANCE III 500 NMR将允许研究人员使用NMR进行化学结构解析和小分子代谢物的全局分析（例如代谢组学）研究将通过允许更高通量的数据收集来提高使用率，并将促进在具有固有低选择性的应用中的研究。此外，新仪器将成为该大学的主力核磁共振光谱仪，并将大大扩展蒙大拿州立大学的核磁共振研究能力，用于获取小分子的多维（1D，2D，3D/nD）杂波（1H，13 C，15 N，31 P）核磁共振光谱。新的仪器，这将取代密歇根州立大学的年龄500核磁共振光谱仪，将提高研究生产力和学生教育。新的工具是绝对必要的，以保持大学的研究生产力，教育质量，和推广使命，并成功地招聘新的教师。