MRI: Acquisition of a cryoprobe- and autosampler-equipped AVANCE III 500 MHz solution NMR

蒙大拿州立大学被授予购买一台Bruker Avance III 500 MHz核磁共振光谱仪，该光谱仪配备了灵敏度增强的Prodigy TM宽带冷冻探头。新的仪器将加强各级的研究和教育。它将使学生能够在新的，强大的小分子核磁共振分析技术方面进行培训，从而极大地有利于研究生和本科生的教育。密歇根州立大学为学生提供最先进的仪器设备方面的直接动手培训，课程范围从夏季本科生研究项目到大二有机实验室课程再到研究生水平的教学项目。新的Avance III 500核磁共振具有增强的功能，还将使他们能够通过远程仪器访问加强少数美国原住民学生的参与，该仪器将为偏远的蒙大拿州部落学院和全州其他小型学院注册的科学课程的学生提供核磁共振谱。配备低温探头的Avance III 500核磁共振将允许研究人员使用核磁共振来阐明化学结构和对小分子代谢物(例如代谢组学)进行全球分析，通过允许更高吞吐量的数据收集来提高使用率，并将促进固有的低选择性应用程序的研究。此外，新仪器将成为该大学的主要核磁共振波谱仪，并将极大地扩展蒙大拿州立大学获取小分子的多维(1D、2D、3D/ND)异核(1H、13C、15N、31P)核磁共振谱的核磁共振研究能力。新仪器将取代密歇根州立大学陈旧的500核磁共振光谱仪，将提高研究生产率和学生教育。新的工具对于维持大学的研究生产力、教育质量和外展使命以及成功招聘新教师是绝对必要的。

An award is made to Montana State University to purchase a Bruker AVANCE III 500 MHz NMR spectrometer equipped with a sensitivity-enhanced Prodigy TM broadband cryoprobe. The new instrument will enhance research and education at all levels. It will strongly benefit student education at both the graduate and the undergraduate level by enabling student training in new, powerful small molecule NMR analytical techniques. MSU provides direct, hands-on training to students in state-of-the-art instrumentation, which is taught in venues ranging from summer undergraduate research programs to sophomore organic laboratory courses to graduate level instructional programs. The new AVANCE III 500 NMR with its enhanced capabilities will also enable them to enhance participation of minority Native American students through remote instrument access that will provide NMR spectra to students enrolled in sciences classes at remote Montana Tribal Colleges and at other small colleges across the state.The cryoprobe-equipped AVANCE III 500 NMR will allow researchers to use NMR for chemical structure elucidation and the global analysis of small molecule metabolites (e.g. metabolomics) research, will enhance usage by permitting higher throughput data collection, and will facilitate studies in applications with inherently low selectivity. In addition, the new instrument will be the workhorse NMR spectrometer for the university and will greatly expand Montana State University's NMR research capabilities for acquisition of multidimensional (1D, 2D, 3D/nD) heteronuclear (1H, 13C, 15N, 31P) NMR spectra of small molecules. The new instrumentation, which will replace MSU's aged 500 NMR spectrometer, will boost research productivity and student education. The new instrument is absolutely essential to maintain the university's research productivity, educational quality, and outreach mission, and for successful recruitment of new faculty.