Rational structure-based drug design of protein tyrosine kinase inhibitors

基于合理结构的蛋白酪氨酸激酶抑制剂药物设计

• 批准号: LP0776674
• 负责人: Prof Jamie Rossjohn
• 金额: $ 40.36万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Projects
• 财政年份: 2007
• 资助国家: 澳大利亚
• 起止时间: 2007-08-15 至 2010-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LP0776674
• 关键词: Rational; structure; based; drug; design

This research project is focussed on understanding the physiological roles of a group of enzymes within the cell, as well as developing therapeutics to combat significant diseases. It will achieve this by developing compounds to enzymes that are implicated in the disease process. The research project represents a continuation of a collaboration between academic researchers at Monash University, and an Australian biotechnology company, Cytopia Ltd.

该研究项目的重点是了解细胞内一组酶的生理作用，以及开发治疗方法来对抗重大疾病。 它将通过开发与疾病过程有关的化合物和酶来实现这一目标。 该研究项目是莫纳什大学学术研究人员与澳大利亚生物技术公司Cytopia Ltd.合作的延续。