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An X-ray crystallographic investigation into co-receptors on T-lymphocytes

An X-ray crystallographic investigation into co-receptors on T-lymphocytes
T 淋巴细胞共受体的 X 射线晶体学研究
批准号：
DP0346007
负责人：
Prof Jamie Rossjohn
金额：
$33.21万
依托单位：
Monash University
依托单位国家：
澳大利亚
项目类别：
Discovery Projects
财政年份：
2003
资助国家：
澳大利亚
项目状态：
已结题
起止时间：
2003-01-01 至 2005-12-31
来源：
https://dataportal.arc.gov.au/RGS/Web/Grants/DP0346007
关键词：
raycrystallographicinvestigationintoco

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英文摘要
T lymphocytes are an indispensable cellular component of the immune system. The normal process of T cell selection in the thymus, and the ability of mature T cells to respond to foreign antigens are governed by receptor recognition and co-receptor mediated events. The co-receptors encompass a wide spectrum of structurally diverse proteins that are involved in adhesion, co-ligation and signal transduction. This proposal aims to investigate, using X-ray crystallography as the primary research tool, co- receptors located on T-lymphocytes. This work will gain fundamental insights into co-receptor function.
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