Exploring therapeutic approaches to combat Coeliac Disease
Exploring therapeutic approaches to combat Coeliac Disease
批准号:
LP110100528
负责人:
Prof Jamie Rossjohn
金额:
$34.77万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Linkage Projects
财政年份:
2011
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2011-01-02 至 2015-12-31
中文摘要
点击翻译按钮获取中文摘要
英文摘要
In Coeliac disease the immune system reacts to ingested wheat protein and attacks the tissue of the small intestine. The wheat protein activates certain immune cells and this initiates a destructive inflammation. In collaboration with the Australian-based company Nexpep, this project aims to develop therapeutics against Coeliac disease.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
An investigation into CD1a, a versatile antigen-presenting molecule
-
批准号:DP220102402
-
项目类别:Discovery Projects
-
资助金额:$41.34万
-
财政年份:2022
-
负责人:Prof Jamie Rossjohn
-
依托单位:
An investigation into T cell immunity towards metabolites
-
批准号:DP220102401
-
项目类别:Discovery Projects
-
资助金额:$52.22万
-
财政年份:2022
-
负责人:Prof Jamie Rossjohn
-
依托单位:
Investigating the atomic structure of an immune cell inhibitory receptor
-
批准号:LP190101290
-
项目类别:Linkage Projects
-
资助金额:$47.65万
-
财政年份:2020
-
负责人:Prof Jamie Rossjohn
-
依托单位:
Investigating the structure of a T cell immune checkpoint molecule
-
批准号:LP160101757
-
项目类别:Linkage Projects
-
资助金额:$25.4万
-
财政年份:2017
-
负责人:Prof Jamie Rossjohn
-
依托单位:
A structural investigation into T cell signalling machines
-
批准号:DP170103822
-
项目类别:Discovery Projects
-
资助金额:$38.95万
-
财政年份:2017
-
负责人:Prof Jamie Rossjohn
-
依托单位:
A molecular investigation into immune function
-
批准号:FL160100049
-
项目类别:Australian Laureate Fellowships
-
资助金额:$205.8万
-
财政年份:2016
-
负责人:Prof Jamie Rossjohn
-
依托单位:
An Automated Protein Nano-Crystallisation Facility
-
批准号:LE160100097
-
项目类别:Linkage Infrastructure, Equipment and Facilities
-
资助金额:$45.01万
-
财政年份:2016
-
负责人:Prof Jamie Rossjohn
-
依托单位:
A structural and molecular investigation into the basic mechanism of T cell receptor complex function
-
批准号:DP140102487
-
项目类别:Discovery Projects
-
资助金额:$45.22万
-
财政年份:2014
-
负责人:Prof Jamie Rossjohn
-
依托单位:
Exploring the immunomodulatory potential of Natural Killer T cells
-
批准号:LP140100920
-
项目类别:Linkage Projects
-
资助金额:$41.66万
-
财政年份:2014
-
负责人:Prof Jamie Rossjohn
-
依托单位:
Australia Fellowship
-
批准号:nhmrc : 1037233
-
项目类别:Research Fellowships
-
资助金额:$266.72万
-
财政年份:2011
-
负责人:Prof Jamie Rossjohn
-
依托单位:
A structural and functional investigation into events within the immunological synapse
-
批准号:DP110103199
-
项目类别:Discovery Projects
-
资助金额:$43.24万
-
财政年份:2011
-
负责人:Prof Jamie Rossjohn
-
依托单位:
A structural investigation into the peptide-loading complex molecular machine
-
批准号:DP0878044
-
项目类别:Discovery Projects
-
资助金额:$83.98万
-
财政年份:2008
-
负责人:Prof Jamie Rossjohn
-
依托单位:
A high throughput protein crystallization & imaging facility
-
批准号:LE0775673
-
项目类别:Linkage Infrastructure, Equipment and Facilities
-
资助金额:$80.02万
-
财政年份:2007
-
负责人:Prof Jamie Rossjohn
-
依托单位:
Rational structure-based drug design of protein tyrosine kinase inhibitors
-
批准号:LP0776674
-
项目类别:Linkage Projects
-
资助金额:$40.36万
-
财政年份:2007
-
负责人:Prof Jamie Rossjohn
-
依托单位:
An investigation into Infection, Immunity & Rational Drug Design
-
批准号:FF0668802
-
项目类别:Federation Fellowships
-
资助金额:$110.84万
-
财政年份:2006
-
负责人:Prof Jamie Rossjohn
-
依托单位:
A Structural Investigation Into Events Within The Immunological Synapse
-
批准号:DP0666539
-
项目类别:Discovery Projects
-
资助金额:$79.45万
-
财政年份:2006
-
负责人:Prof Jamie Rossjohn
-
依托单位:
Rational structure-based drug design of protein tyrosine kinase inhibitors
-
批准号:LP0454285
-
项目类别:Linkage Projects
-
资助金额:$83.56万
-
财政年份:2004
-
负责人:Prof Jamie Rossjohn
-
依托单位:
An X-ray crystallographic investigation into co-receptors on T-lymphocytes
-
批准号:DP0346007
-
项目类别:Discovery Projects
-
资助金额:$33.21万
-
财政年份:2003
-
负责人:Prof Jamie Rossjohn
-
依托单位:
An X-ray crystallographic investigation into the structural basis of T-cell allorecognition
-
批准号:nhmrc : 236825
-
项目类别:NHMRC Project Grants
-
资助金额:$29.41万
-
财政年份:2003
-
负责人:Prof Jamie Rossjohn
-
依托单位:
Structural studies on the mitochondrial protein import machinery.
-
批准号:DP0212024
-
项目类别:Discovery Projects
-
资助金额:$8.34万
-
财政年份:2002
-
负责人:Prof Jamie Rossjohn
-
依托单位:
国内基金
海外基金
芍药苷靶向α-烯醇化酶治疗实验性自身免疫性脑脊髓炎的机制研究
-
批准号:82371809
-
项目类别:面上项目
-
资助金额:49.00万元
-
批准年份:2023
-
负责人:聂红
-
依托单位:
新型小分子蛋白—人肝细胞生长因子三环域(hHGFK1)抑制破骨细胞及治疗小鼠骨质疏松的疗效评估与机制研究
-
批准号:82370885
-
项目类别:面上项目
-
资助金额:49.00万元
-
批准年份:2023
-
负责人:姚晨
-
依托单位:
HER2特异性双抗原表位识别诊疗一体化探针研制与临床前诊疗效能研究
-
批准号:82372014
-
项目类别:面上项目
-
资助金额:48.00万元
-
批准年份:2023
-
负责人:魏伟军
-
依托单位: