A structural investigation into the peptide-loading complex molecular machine

肽负载复杂分子机器的结构研究

• 批准号: DP0878044
• 负责人: Prof Jamie Rossjohn
• 金额: $ 83.98万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2008
• 资助国家: 澳大利亚
• 起止时间: 2008-01-02 至 2012-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP0878044
• 关键词: structural; investigation; into; peptide; loading

The proposed research program, using laboratory-based and synchrotron-based radiation, will provide fundamental insight into a process central to immunity, namely antigen presentation. Investigating the process of Antigen presentation is important, as it will further our understanding how a cell is "ear-marked" for being infected by viruses or bacteria. Such knowledge will increase Australia's international research standing.

拟议的研究计划，使用基于实验室和同步辐射，将提供基本的洞察力的过程中，中央免疫，即抗原呈递。 研究抗原呈递的过程很重要，因为它将进一步了解细胞如何被病毒或细菌感染。这些知识将提高澳大利亚的国际研究地位。