Development of a heat-melting method for stent graft suturing
Development of a heat-melting method for stent graft suturing
批准号:
24659638
负责人:
NOISHIKI Yasuharu
金额:
$2.41万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2012
资助国家:
日本
项目状态:
已结题
起止时间:
2012-04-01 至 2014-03-31
中文摘要
支架移植存在几个亟待解决的问题。其中之一是缝合结扎后的磨损问题。可膨胀的金属线通过缝合线固定,织物通过缝合线嫁接,缝合线由聚酯纤维等聚合物材料制成。由于聚合物材料通常很滑,需要三次以上的结扎才能防止结子松动,从而导致体积增大。通常,细长的支架移植物不需要笨重的结节。为了解决这一问题,我们开发了一种由普通涤纶纤维涂覆特殊聚合物制成的混合缝合线,该缝合线的熔点在180~220摄氏度左右,而普通涤纶纤维在260摄氏度熔化。使用我们的特殊缝线,当移植物在220摄氏度加热时,被测试的支架移植物的结扎部位的所有结都被聚合物熔化固定。因此,支架移植物加热220摄氏度后,磨损问题就完全解决了。
英文摘要
Stent grafts have several problems which should be solved urgently. One of them is a fraying problem after suture ligation. Expandable metal wires are fixed by sutures with fabric grafts by sutures, which are made of polymer materials such as polyester fibers. As polymer materials are usually slippery, more than three-time ligations are required to prevent the knots become loose, which resulted in bulky. Generally bulky knots are not desirable for slim stent grafts. In order to solve the problem, we have developed a hybrid suture made of regular polyester fibers coated with special polymer having a lower melting point, around 180~220 Celsius,while regular polyester fibers melts at 260 Celsius. Using our special sutures, all the knots of ligated sites of the tested stent graft were fixed by meltdown of the polymer when the graft was heated at 220 Celsius. Consequently, the fraying problem is completely overcome after 220 Celsius heating of stent grafts.
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Elevated microsatellite alterations at selected tetra-nucleotide (EMAST) in non-small cell lung cancers – a potential determinant of susceptibility to multiple malignancies.
非小细胞肺癌中选定四核苷酸 (EMAAST) 的微卫星改变升高——这是多种恶性肿瘤易感性的潜在决定因素。
DOI:
--
发表时间:
2013
期刊:
Int. J. Clin. Exp Patho
影响因子:
--
作者:
[H. Arai, et al]
通讯作者:
et al
Elevated microsatellite alterations at selected tetra-nucleotide (EMAST) in non-small cell lung cancers - a potential determinant of susceptibility to multiple malignancies
非小细胞肺癌中选定四核苷酸(EMAAST)的微卫星改变升高——多种恶性肿瘤易感性的潜在决定因素
DOI:
--
发表时间:
2013
期刊:
Int. J. Clin. Exp Patho
影响因子:
--
作者:
[H. Arai, K Okudera, H. Oshiro, N. Komitsu, H. Mitsui, T. Nishi, M. Tsuboi, A. Nozawa, Y. Noishiki, K. Ohhashi, K. Inui,M.Masuda]
通讯作者:
K. Inui,M.Masuda
Plasmodium induced by SU6656, an Sre family kinase inhibitor, in accompanied by a contractile ring defect.
由 Sre 家族激酶抑制剂 SU6656 诱导的疟原虫,伴有收缩环缺陷。
DOI:
--
发表时间:
2012
期刊:
Cell Biochem. Func
影响因子:
--
作者:
[K. Yoshida, et al]
通讯作者:
et al
癒着防止膜の現状。水の動きと細胞の動き
防粘连膜的现状。
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[野一色泰晴, 伊藤博]
通讯作者:
伊藤博
人工血管壁における再生内膜平滑筋細胞配列の走査電顕観察
扫描电镜观察人工血管壁再生内膜平滑肌细胞排列
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
[野一色泰晴, 伊藤博, 跡部好敏, 船越健悟]
通讯作者:
船越健悟
共 10 条
Fundamental study of an anti-adhesive membrane for thoracic surgeries
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批准号:22390268
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$12.48万
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财政年份:2010
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负责人:NOISHIKI Yasuharu
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依托单位:
Development of a coated vascular prosthesis cope with BSE problems
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批准号:17390384
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$10.21万
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财政年份:2005
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负责人:NOISHIKI Yasuharu
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依托单位:
FUNDAMENTAL STUDY FOR VASCULAR PROSTHESIS THAT CAN ABSORBE ENDOGENOUS CYTOKINES
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批准号:11470249
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项目类别:Grant-in-Aid for Scientific Research (B).
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资助金额:$9.6万
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财政年份:1999
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负责人:NOISHIKI Yasuharu
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依托单位:
Fundamental study for autocrine artificial
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批准号:09480256
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$8.9万
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财政年份:1997
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负责人:NOISHIKI Yasuharu
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依托单位:
FUNDAMENTAL STUDY FOR DEVELOPMENT OF AUTOCRINE ARTIFICIAL ORGANS
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批准号:07558259
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$0.83万
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财政年份:1995
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负责人:NOISHIKI Yasuharu
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依托单位:
FUNDAMENTAL STUDY FOR VASCULAR PROSTHESIS WITH AUTOLOGOUS BONE MARROW TRANSPLANTATION FOR CORONARY ARTERY BY PASS GRAFTING
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批准号:07457260
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$4.93万
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财政年份:1995
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负责人:NOISHIKI Yasuharu
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依托单位:
Fundamental study of development of autologous tissue fragmented vascular prosthesis for A-C bypass use
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批准号:04557060
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项目类别:Grant-in-Aid for Developmental Scientific Research (B)
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资助金额:$9.98万
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财政年份:1992
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负责人:NOISHIKI Yasuharu
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依托单位:
Development of a safety method to utilize a high porous fabric vascular prosthesis and neointimal formation on the prosthesis wall with this method
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批准号:04454348
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项目类别:Grant-in-Aid for General Scientific Research (B)
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资助金额:$4.48万
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财政年份:1992
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负责人:NOISHIKI Yasuharu
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依托单位:
Basic research for long-term evaluation of a growable vascular prosthesis and safetyness for clinical use.
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批准号:01870060
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项目类别:Grant-in-Aid for Developmental Scientific Research
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资助金额:$6.27万
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财政年份:1989
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负责人:NOISHIKI Yasuharu
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依托单位:
Fundamental study for the development of a low porous vascular graft which has a high healing property, soft and pliable characteristics.
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批准号:62570638
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.41万
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财政年份:1987
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负责人:NOISHIKI Yasuharu
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依托单位:
Fundamental research for the development of a growable vascular graft
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批准号:61870056
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项目类别:Grant-in-Aid for Developmental Scientific Research
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资助金额:$8.06万
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财政年份:1986
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负责人:NOISHIKI Yasuharu
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依托单位:
海外基金