权益分类	功能权益	普通用户	{{item.name}}会员
{{category.name}}	{{benefitItem.name}}

Development of a heat-melting method for stent graft suturing

热熔覆膜支架缝合方法的开发

基本信息

批准号：
24659638
负责人：
NOISHIKI Yasuharu
金额：
$ 2.41万
依托单位：
Yokohama City University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Challenging Exploratory Research
财政年份：
2012
资助国家：
日本
起止时间：
2012-04-01 至 2014-03-31
项目状态：
已结题

项目摘要

Stent grafts have several problems which should be solved urgently. One of them is a fraying problem after suture ligation. Expandable metal wires are fixed by sutures with fabric grafts by sutures, which are made of polymer materials such as polyester fibers. As polymer materials are usually slippery, more than three-time ligations are required to prevent the knots become loose, which resulted in bulky. Generally bulky knots are not desirable for slim stent grafts. In order to solve the problem, we have developed a hybrid suture made of regular polyester fibers coated with special polymer having a lower melting point, around 180~220 Celsius,while regular polyester fibers melts at 260 Celsius. Using our special sutures, all the knots of ligated sites of the tested stent graft were fixed by meltdown of the polymer when the graft was heated at 220 Celsius. Consequently, the fraying problem is completely overcome after 220 Celsius heating of stent grafts.

支架移植有几个亟待解决的问题。其中之一是缝合结扎后的磨损问题。可膨胀金属丝通过缝合线固定，织物移植物通过缝合线固定，织物移植物由聚酯纤维等高分子材料制成。由于聚合物材料通常很滑，需要三次以上的打结来防止结变松，从而导致体积过大。一般来说，对于细长的支架移植来说，笨重的结是不可取的。为了解决这个问题，我们开发了一种混合缝线，由普通聚酯纤维涂覆特殊聚合物制成，熔点较低，约为180~220摄氏度，而普通聚酯纤维的熔点为260摄氏度。使用我们的特殊缝合线，当移植物在220摄氏度加热时，所有被测试的支架的结扎部位的结都被聚合物熔化固定。因此，在220摄氏度的支架加热后，磨损问题完全被克服。

项目成果

期刊论文数量（12）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Elevated microsatellite alterations at selected tetra-nucleotide (EMAST) in non-small cell lung cancers – a potential determinant of susceptibility to multiple malignancies.

非小细胞肺癌中选定四核苷酸 (EMAAST) 的微卫星改变升高——这是多种恶性肿瘤易感性的潜在决定因素。

DOI：
发表时间：
2013
期刊：
Int. J. Clin. Exp Patho
影响因子：
0
作者：
H. Arai;et al
通讯作者：
et al

Elevated microsatellite alterations at selected tetra-nucleotide (EMAST) in non-small cell lung cancers - a potential determinant of susceptibility to multiple malignancies

非小细胞肺癌中选定四核苷酸（EMAAST）的微卫星改变升高——多种恶性肿瘤易感性的潜在决定因素

DOI：
发表时间：
2013
期刊：
Int. J. Clin. Exp Patho
影响因子：
0
作者：
H. Arai;K Okudera;H. Oshiro;N. Komitsu;H. Mitsui;T. Nishi;M. Tsuboi;A. Nozawa;Y. Noishiki;K. Ohhashi;K. Inui,M.Masuda
通讯作者：
K. Inui,M.Masuda

Plasmodium induced by SU6656, an Sre family kinase inhibitor, in accompanied by a contractile ring defect.

由 Sre 家族激酶抑制剂 SU6656 诱导的疟原虫，伴有收缩环缺陷。