New Approaches for Creating New Phosphines and Their Applications

制造新膦的新方法及其应用

• 批准号: 18065014
• 负责人: OSHIMA Koichiro
• 金额: $ 21.5万
• 依托单位: Kyoto University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research on Priority Areas
• 财政年份: 2006
• 资助国家: 日本
• 起止时间: 2006 至 2009
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-18065014/
• 关键词: 選択的合成・反応; ホスフィン配位子; 環化付加; インドール; 立体障害; 鈴木カップリング; パラジウム触媒; ホスフィン; 均一系分子触媒; 配位子; 協奏機能; かさ高い配位子; 交差カップリング反応; 二座配位子; ヒドロホスフィン化; 1-アルキニルホスフィン

Due to the importance of organophosphines as ligands for transition metal catalysts, development of efficient methods for the synthesis of new phosphines is very important. We recognized 1-alkynylphosphines and their derivatives as useful precursors for creation of new phosphines. Chemical modifications of the carbon-carbon triple bonds, including nucleophilic addition and cycloaddition, led to a wide range of new useful phosphines that are otherwise difficult to synthesize.

由于有机膦作为过渡金属催化剂配体的重要性，开发合成新型膦的有效方法是非常重要的。我们认识到1-炔基膦及其衍生物是生成新膦的有用前体。碳碳三键的化学修饰，包括亲核加成和环加成，导致了广泛的新的有用的磷化氢，否则很难合成。

项目成果

Synthesis of bulky phosphines by rhodium-catalyzed formal [2+2+2] cycloaddition reactions of tethered diynes with 1-alkynylphosphine sulfides.

• DOI: 10.1021/ja071622o
• 发表时间: 2007-05
• 期刊: Journal of the American Chemical Society
• 影响因子: 15
• 作者: Azusa Kondoh;H. Yorimitsu;K. Oshima

Copper-catalyzed anti-Hydrophosphination Reaction of 1-Alkynylphosphines with Diphenylphosphine Providing (Z)-1,2-Diphosphino-l-alkenes

铜催化 1-炔基膦与二苯基膦的反氢膦化反应生成 (Z)-1,2-二膦基-1-烯烃

• 发表时间: 2007
• 期刊: Journal of the American Chemical Society 129(in press)
• 作者: Azusa Kondoh;Hideki Yorimitsu;Koichiro Oshima
• 通讯作者: Koichiro Oshima

Copper-catalyzed anti-hydrophosphination reaction of 1-alkynylphosphines with diphenylphosphine providing (Z)-1,2-diphosphino-1-alkenes

• DOI: 10.1021/ja070048d
• 发表时间: 2007-04-04
• 期刊: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
• 影响因子: 15
• 作者: Kondoh, Azusa;Yorimitsu, Hideki;Oshima, Koichiro
• 通讯作者: Oshima, Koichiro

Synthesis of bulky arylphosphanes by rhodium-catalyzed formal [2+2+2] cycloaddition reaction and their use as ligands.

• DOI: 10.1002/asia.200800102
• 发表时间: 2008-09
• 期刊: Chemistry, an Asian journal
• 作者: Takayuki Kobatake;Azusa Kondoh;S. Yoshida;H. Yorimitsu;K. Oshima

Synthesis of Bulky Phosphines by Rhodium-Catalyzed Formal [2+2+2] Cycloaddition Reactions of Tethered Diynes with 1-Alkynylphosphine

铑催化束缚二炔与 1-炔基膦的缩甲醛 [2 2 2] 环加成反应合成大体积膦

• 发表时间: 2007
• 期刊: Journal of the American Chemical Society 129
• 作者: Azusa Kondoh;Hideki Yorimitsu;and Koichiro Oshima
• 通讯作者: and Koichiro Oshima