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Studies on the control of hantavirus infection and rodent

汉坦病毒感染及啮齿类动物防治研究

基本信息

批准号：
08044227
负责人：
ARIKAWA Jiro
金额：
$ 7.87万
依托单位：
Hokkaido University
依托单位国家：
日本
项目类别：
Grant-in-Aid for international Scientific Research
财政年份：
1996
资助国家：
日本
起止时间：
1996 至 1997
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-08044227/
关键词：
Hemorrhagic fever with renal syndrome HFRS hantavirus vaccine zoonosis epidemiology rodent virus infection ウイルス感染

项目摘要

Japanese investigator, Dr. Sugiyama carried out a epizootiologicstudy of wild rodents at Beijing and Xian city. A total of 100 rodents were captured from the two regions and were examined for their antibody and antigen distribution.Chinese investigator, Dr. Li, stayed at Japanese research institution for examining genetic comparison among Chinese hantaviruses obtained from above materials. He examined partial nucleotide sequence of two Chinese isolates and showed the higher relationship to Korean isolates than to Japanese one.Finish investigator, Dr. Vaheri, visited at Japanese investigator's institutions for information exchange regarding the epidemiologicand epizootiologicsituations of hantavirus infection in northern part of Europe.Head investigator (Dr. Arikawa) and Japanese investigator (Dr. Morimatsu) visited at Centers for Disease Control and Prevention for information exchange regarding the prevalence of hantavirus infection over the world with American investigator Dr. Peters. … More Head investigator, Dr. Arikawa and Japanese investigator, Dr. Takashima, visited institutions in Austria and Slovakia to obtain information about epidemiologicsituation of hantavirus infection in Eastern Europe.Japanese investigators, Drs. Kariwa and Morimatsu visited Glasgow university to obtain technical information regarding the genetic reassortant virus and reverse genetic.Japanese head investigator, Dr. Arikawa and investigators, Drs. Takashima, Kariwa, Morimatsu visited Korean investigator, Dr. Lee at Asan Life Science Institute at Seoul Korea for information exchange regarding the comparison of variabilities of Japanese and Korean isolates.Chinese investigator, Dr. Wang stayed at head investigator's institute (Hokkaido University School of Medicine) for 6 months and accomplished antigenic and genetic comparison among 50 isolates.Chinese investigator, Dr. Chen, visited institutions of Japanese investigators at Sapporo and Tokyo information exchange about relation between ecology of wild rodents and prevalence of hantavirus infection. Less

日本调查员杉山博士在北京和西安对野生啮齿动物进行了一项动物动物学研究。从这两个地区捕获了100只啮齿动物，并对它们的抗体和抗原分布进行了检查。中国研究人员李博士留在日本研究机构，对从上述材料获得的中国汉坦病毒进行基因比对。他检查了两个中国分离株的部分核苷酸序列，发现与韩国分离株的亲缘关系高于与日本分离株的亲缘关系。最终调查员Vaheri博士访问了日本调查机构，就欧洲北部地区汉坦病毒感染的流行病学和流行病学情况进行了信息交流。首席调查员Arikawa博士和日本调查人员森松博士访问了疾病控制和预防中心，与美国调查人员彼得斯博士就全球汉坦病毒感染的流行情况进行了信息交流。…更多首席研究员Arikawa博士和日本研究员Takashima博士访问了奥地利和斯洛伐克的机构，了解东欧汉坦病毒感染的流行病学情况。日本调查人员Kariwa博士和Morimatsu博士访问了格拉斯哥大学，获得了关于基因重组病毒和反向基因的技术信息。日本首席研究员Arikawa博士和调查人员Takashima博士、Kariwa博士、Morimatsu博士访问了韩国研究员Lee博士，就日本和韩国分离株的变异进行了比较。中国调查员，王博士在首席调查员研究所(北海道大学医学院)停留了6个月，完成了50个分离株的抗原性和基因比对。中国调查员陈博士访问了札幌和东京的日本调查机构，就野生啮齿动物生态与汉坦病毒感染流行之间的关系进行了信息交流。较少