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Studies on the control of hantavirus infection and rodent

Studies on the control of hantavirus infection and rodent
汉坦病毒感染及啮齿类动物防治研究
批准号:
08044227
负责人:
ARIKAWA Jiro
金额:
$7.87万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for international Scientific Research
财政年份:
1996
资助国家:
日本
项目状态:
已结题
起止时间:
1996 至 1997

项目摘要

项目成果

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中文摘要
翻译
日本研究者杉山博士在北京和西安进行了一项野生啮齿动物流行病学研究。从两个地区共捕获100只啮齿动物,检测其抗体和抗原分布,中国研究员李博士留在日本研究机构,对从上述材料中获得的中国汉坦病毒进行遗传比较。他检查了两个中国分离株的部分核苷酸序列,显示与韩国分离株的关系高于日本分离株。访问日本研究机构,就欧洲北方汉他病毒感染的流行病学和动物流行病学情况交换信息。(Dr. Arikawa)和日本研究者(Dr. Morimatsu)访问了美国疾病控制和预防中心,与美国研究者Dr. Peters就汉坦病毒感染在全球的流行情况进行了信息交流。 ...更多信息 首席研究员Arikawa博士和日本研究员Takashima博士访问了奥地利和斯洛伐克的机构,以获得关于东欧汉坦病毒感染的流行病学情况的信息。日本研究员Kariwa博士和Morimatsu博士访问了格拉斯哥大学,以获得关于遗传抵抗病毒和逆转遗传的技术信息。日本首席研究员Arikawa博士和研究员Takashima博士,Kariwa博士,Morimatsu访问了韩国研究者,首尔Asan生命科学研究所的Lee博士,就日本和韩国分离株的变异性比较进行信息交流。中国研究者,Wang博士留在首席研究者研究所(北海道大学医学院)进行了6个月的研究,并在50个分离株中完成了抗原和遗传比较。访问了日本调查人员在札幌和东京的研究机构,就野生啮齿动物生态与汉坦病毒感染流行之间的关系进行了信息交流。少
英文摘要
Japanese investigator, Dr. Sugiyama carried out a epizootiologicstudy of wild rodents at Beijing and Xian city. A total of 100 rodents were captured from the two regions and were examined for their antibody and antigen distribution.Chinese investigator, Dr. Li, stayed at Japanese research institution for examining genetic comparison among Chinese hantaviruses obtained from above materials. He examined partial nucleotide sequence of two Chinese isolates and showed the higher relationship to Korean isolates than to Japanese one.Finish investigator, Dr. Vaheri, visited at Japanese investigator's institutions for information exchange regarding the epidemiologicand epizootiologicsituations of hantavirus infection in northern part of Europe.Head investigator (Dr. Arikawa) and Japanese investigator (Dr. Morimatsu) visited at Centers for Disease Control and Prevention for information exchange regarding the prevalence of hantavirus infection over the world with American investigator Dr. Peters. … More Head investigator, Dr. Arikawa and Japanese investigator, Dr. Takashima, visited institutions in Austria and Slovakia to obtain information about epidemiologicsituation of hantavirus infection in Eastern Europe.Japanese investigators, Drs. Kariwa and Morimatsu visited Glasgow university to obtain technical information regarding the genetic reassortant virus and reverse genetic.Japanese head investigator, Dr. Arikawa and investigators, Drs. Takashima, Kariwa, Morimatsu visited Korean investigator, Dr. Lee at Asan Life Science Institute at Seoul Korea for information exchange regarding the comparison of variabilities of Japanese and Korean isolates.Chinese investigator, Dr. Wang stayed at head investigator's institute (Hokkaido University School of Medicine) for 6 months and accomplished antigenic and genetic comparison among 50 isolates.Chinese investigator, Dr. Chen, visited institutions of Japanese investigators at Sapporo and Tokyo information exchange about relation between ecology of wild rodents and prevalence of hantavirus infection. Less
期刊论文(10)
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科研奖励(0)
会议论文
Yoshimatsu, K.: "Western blotting using recombinant Hantaan virus nucleocapsid protein expressed in silkworm as a serological confirmation of hantavirus infection in human sera." Journal of Veterinary Medical Science. 58. 71-74 (1996)
Yoshimatsu, K.:“使用在家蚕中表达的重组汉坦病毒核衣壳蛋白进行蛋白质印迹,作为人类血清中汉坦病毒感染的血清学确认。”
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通讯作者:
Yoshimatsu, K: "Hantavirus infection in SCID mice" Journal of Veterinary Medical Scince. 59. 863-868 (1997)
Yoshimatsu, K:“SCID 小鼠的汉坦病毒感染”《兽医医学杂志》。
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通讯作者:
Kariwa, H: "Urine-associated transmission of Seoul virus among rats"Archives of Virology. 143. 15-24 (1998)
Kariwa, H:“首尔病毒在大鼠中与尿液相关的传播”病毒学档案。
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通讯作者:
Kikuchi,M: "Characterization of neutralizing monoclonal antibody escape mutants of Hantaan virus 76118"Archives of Virology. 143. 73-83 (1998)
Kikuchi,M:“汉坦病毒 76118 中和单克隆抗体逃逸突变体的表征”病毒学档案。
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共 8 条
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      ARIKAWA Jiro
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